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Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
of Old and New Potassium-Binding ... #Binding #KBinders ... #Kayexelate #Comparison ... #Table #Pharmacology ... #Patiromer #HyperKalemia
Antiseizure Drugs 
Sodium Channel Blockers: Carbamazepine, Oxcarbazepine, Eslicarbazepine, Lamotrigine, Lacosamide, Phenytoin, fosphenytoin
Broad Spectrum: Valproate, Levetiracetam, Brivaracetam,
Antiseizure Drugs ... Sodium Channel Blockers ... Tiagabine, Vigabatrin Potassium ... medications #epilepsy #pharmacology ... #comparison #table
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... of aspiration #Potassium ... #Binding #Hyperkalemia ... #medications #pharmacology ... #table #comparison
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Digoxin Pharmacology ... works by directly binding ... - When digoxin blocks ... - Hyperkalemia ( ... Pathophysiology #cardiology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
ARBs, NSAIDs, β-blockers ... injury, ischemia, hemolysis ... Elimination (see Table ... Treatments: • K-Binding ... Management #Treatment #potassium
Clinically Significant Cardiovascular Drug-Drug Interactions With OTC Supplements and Herbal Products
Angiotensin-Converting Enzyme Inhibitors (ACEIs)
 • Night-blooming
Cardiovascular Drug-Drug ... Licorice - Causes hypokalemia ... Antiarrhythmic Drugs ... supplementals #herbal #pharmacology ... #DDI #table #cardiology
Sedative-Hypnotic Drugs
Benzodiazepines:
 - Bind to specific GABAA receptor subunits at central nervous system (CNS) neuronal synapses
Sedative-Hypnotic Drugs ... Antagonists: - Blocks ... binding of orexins ... #medications #pharmacology ... #comparison #table