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hematology algorithm causes management nonpalpable petechiae petechial rash rheumatology workup activation agglutinin cardiology classification cold dehydrogenase disease effusion elevated hemopericardium
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Volume (MCV) - Differential ... Diagnosis Algorithm ... Hypersplenism • Secondary ... #Differential # ... #Causes #Hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Diagnosis Secondary ... malignancies • Anemia ... iron deficiency, hemolysis ... , hemorrhage) ... #hematology #secondary
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Diagnosis Algorithm ... bartonella (oroya fever ... #Anemia #Differential
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
AIHA Primary Secondary ... Diagnosis: • hemolytic ... younger pts) Differential ... Symptoms: High fevers ... #anemia #hematology
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
Dehydrogenase (LDH) - Differential ... Diagnosis Framework ... meningitis • Cerebral hemorrhage ... myocarditis, rheumatic fever ... #diagnosis #Laboratory
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
red to purple, hemorrhagic ... DIC/TTP/HUS - Hemolytic ... anemia - Splenomegaly ... mountain spotted fever ... #Diagnosis #hematology
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Nail Disorders secondary ... Iron deficiency anemia ... Discoloration - Splinter hemorrhages ... #dermatology #Differential ... #Diagnosis #Algorithm
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
in most cases; hemorrhage ... result in severe anemia ... anemia Indirect ... WBC count and differential ... #Workup #Hematology
Hemorrhagic Pericardial Effusions (Hemopericardium)- Differential Diagnosis Framework IATROGENIC DISEASE Secondary to invasive cardiac procedures NONIATROGENIC • Malignancy (e.g., metastatic spread:
Hemopericardium)- Differential ... Diagnosis Framework ... IATROGENIC DISEASE Secondary ... amyloidosis • Uremia ... Mediterranean fever
Fever Patterns - Differential Diagnosis Framework Continuous Fever: Temp > 38°C with only 1 degree fluctuation in 24
Differential Diagnosis ... with profound hemolysis ... Leptospirosis • Viral hemorrhagic ... #Patterns #Differential ... #Diagnosis #intermittent
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