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Biochemistry and Metabolism of Bilirubin Hemolysis → Hemoglobin → Heme → Biliverdin → Unconjugated Bilirubin (a.k.a. "indirect
into bile via hepatic ... interchangeably for routine clinical ... Biochemistry #Metabolism #pathophysiology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook Presentation: • Plts ↓50% (nadir
Heparin Induced ... ♀, ↑Age, ESRD Pathophysiology ... Diagnosis: • Clinical ... • Start non-heparin ... A/C if clinical
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... organ damage Clinical ... dysfunction (25%) • Hepatic ... deficiency) • HIT: Heparin-PF4 ... 100mg/dL) - Heparin
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... accumulation of clinical ... Assessment • Clinical ... +++ (Plt, Hb), Hepatic
Type II Hypersensitivity: Pathogenesis and clinical findings Definition: When antigens bind to the body's cell surfaces, forming
Pathogenesis and clinical ... Example: drug (i.e. heparin ... Allergy #Immunology #pathophysiology
Thiamine Deficiency - Differential Diagnosis Framework and Clinical Manifestations Causes of Thiamine Deficiency: • Poor intake: - Diets
Framework and Clinical ... liver failure: Hepatic ... beriberi #nutrition #pathophysiology
Hepatic Portal Venous System Drainage Anatomy 1) Most of the blood from abdominal organs goes into the
Hepatic Portal Venous ... goes into the hepatic ... capillaries of hepatic ... IVC using the hepatic ... System #Anatomy #Pathophysiology
Pathogenesis of Edema in Hepatic Cirrhosis #Edema #Cirrhosis #Pathophysiology
Pathogenesis of Edema in Hepatic ... Edema #Cirrhosis #Pathophysiology
Mechanism of Action of Bile Acid Sequestrants Bile Acid Sequestrants → ↓ Hepatic Bile Acid Pool →
Sequestrants → ↓ Hepatic ... Acid Pool → ↑ Hepatic ... sequestration #pathophysiology
Non-Cirrhotic Portal Fibrosis (NCPF) vs Extra-Hepatic Portal Vein Obstruction (EHPVO) By Sharanya Kaushik @sharanyakaushik and Vallabh Shet
NCPF) vs Extra-Hepatic ... #NCPF #EHPVO #pathophysiology
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