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HepatoRenal Syndrome - Pathophysiology

Dr. Edgar V. Lerma @edgarvlermamd - Nephrology Secrets https://amzn.to/34t5DgJ

#HRS #HepatoRenal #Syndrome #Pathophysiology #Diagnosis
HepatoRenal Syndrome ... 34t5DgJ #HRS #HepatoRenal ... Pathophysiology #Diagnosis
Clinical manifestations of acute liver failure 

Brain: 
Hepatic encephalopathy,  
Cerebral edema,  
Intracranial hypertension,
and adrenals: Hepatorenal ... syndrome, Hepatoadrenal ... Signs #Symptoms #Diagnosis
 End Stage Liver Disease (Cirrhosis) - Complications 
 • Ascites
 • Esophageal Varices
 • Hepatic
Syndrome (HPS) • Hepatorenal ... Complications #diagnosis
Complications of Portal Hypertension
 • Hepatic Encephalopathy
 • Pulmonary: Hepatopulmonary syndrome, Portopulmonary hypertension, Hepatic hydrothorax
 •
Pancytopenia • Renal: Hepatorenal ... Complications #hepatology #diagnosis
Hepatorenal Syndrome Diagnosis
 • ↑ in serum Cr of ≥ 0.3mg/dL above baseline
Hepatorenal Syndrome ... Diagnosis • ↑ ... EricsMedicalLectures/ #Hepatorenal ... #Syndrome #diagnosis
Hepatorenal Syndrome (HRS) - Diagnostic Criteria
HRS-AKI (Acute: previously known as HRS Type 1)
 • ↑ Creatinine
Hepatorenal Syndrome ... (HRS) - Diagnostic ... drkeithsiau #HRS #Hepatorenal ... #Syndrome #diagnosis
Approach to the Hospitalized Patient with Cirrhosis
1) Recognize and Manage Decompensation
 • Ascites
 • Variceal Bleeding
Alcoholic Hepatitis • Hepatorenal ... inpatient #Cirrhosis #diagnosis
Hepatorenal Syndrome - Diagnosis and Management Summary
Who gets HRS?
 • Decompensated cirrhosis
 • Typically with existing
Hepatorenal Syndrome ... - Diagnosis and ... HershShroff #Hepatorenal ... Syndrome #HRS #Diagnosis
Acute Kidney Injury - Classification
Prerenal:
 • Dehydration
 • Heart failure (a.k.a. cardiorenal syndrome)
 • Liver failure
failure (a.k.a. hepatorenal ... Classification #diagnosis
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Prerenal:
 • Due to true volume loss or decreased
- Differential Diagnosis ... : cardiorenal, hepatorenal ... #Differential #Diagnosis