225 results
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Hepatocellular Liver ... liver failure 1) Hepatocellular ... with AST/ALT) Hepatocellular ... • Infections: Hepatitis ... Transaminitis #LFTs #hepatitis
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Differential Diagnosis Hepatocellular ... • Infectious: Hepatitis ... NAFLD, Autoimmune hepatitis ... Celiac Disease Hepatocellular ... Sepsis, Viral Hepatitis
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
ALP) • R > 5: Hepatocellular ... Check Acute viral hepatitis ... Check Acute viral hepatitis ... ALP: Typical of hepatocellular ... Chronic viral hepatitis
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Thrombosis, Emboli Hepatocellular ... Autoimmune: Autoimmune hepatitis ... ALP: Typical of hepatocellular ... Chronic viral hepatitis ... liver #injury #hepatitis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
alternative causes • Hepatocellular ... ascites), Chronic hepatitis ... • Autoimmune hepatitis
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
Autoimmune Hepatitis ... - Typically hepatocellular ... Other Etiology of Hepatitis ... #Autoimmune #Hepatitis
Classification of Jaundice
Unconjugated hyperbilirubinemia (predominantly indirect bilirubin)
 • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
pregnancy) • Hepatocellular ... hepatocyte damage (eg, hepatitis ... postoperative jaundice) Hepatocellular
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
• Early acute hepatitis ... • Ischemic hepatitis ... • Acute Hepatocellular ... distinguishes ischemic hepatitis ... 1.5) from viral hepatitis
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
- Alcoholic hepatitis ... metastases - Hepatocellular
Alcohol-related liver disease algorithm. 

In patients in whom alcohol is suspected to be the main injurious
γ-glutamyltransferase; HCC, hepatocellular ... algorithm #ARLD #Hepatitis