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Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... infiltrates maternal hepatocytes ... = nonspecific (nausea ... liver transplant center ... iMedEducation #AFLP
Causes of AKI in Pregnancy - Differential Diagnosis Creatinine - Platelets - Transaminases - LDH - PT/PTT
Causes of AKI in ... Nephritis • AFLP ... Differential #Diagnosis #Causes
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
• Pregnancy - AFLP ... • Pancreatic cancer ... Diagnosis #Algorithm #Causes
Causes of Secondary IgA Nephropathy - Differential Diagnosis Algorithm • GI disorders: Celiac disease, Crohn's disease,
Causes of Secondary ... Schistosomiasis • Cancers ... Lymphomas, RCC, Lung Cancer ... #Nephropathy #Causes
Inherited Colorectal Cancer (CRS) Syndromes Adenomatous Polyposis Syndromes: • Familial Adenomatous Polyposis (FAP), Attenuated FAP (AFAP), MUTYH
Inherited Colorectal Cancer ... Attenuated FAP (AFAP ... Inherited #Colorectal #Cancer
Causes of Iron Deficiency • Inadequate Intake: Vegetarian/vegan diet, Malnutrition • Increased Body Needs: Infants/preschoolers, Pregnancy,
Causes of Iron Deficiency ... without anaemia): GI cancers ... Disease (IBD, cancer ... differential #diagnosis #causes
Causes of Hyperferritinemia - Differential Diagnosis Ferritin > 1000 Ferritin is the storage form of iron. Increased hepcidin
Causes of Hyperferritinemia ... leaving enterocytes, hepatocytes ... Most Common Causes ... 1% Most Common Causes ... is an uncommon cause
Upper and Lower Causes of GI Bleed Upper: • Esophagus: Tear (Mallory Weiss, Boerhaave syndrome), Variceal, Esophagitis,
Upper and Lower Causes ... , Esophagitis, Cancer ... Duodenitis, AVM, Cancer ... Diverticular, Cancer ... differential #diagnosis #Causes
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
of Pregnancy (AFLP ... child * Severe cases ... TTPHUS #HELLP #AFLP
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
ALP enzyme- Discovered ... in 1923 Low ALP ... 1948 by Rathbun ALP ... Most cases diagnosed ... Phosphatase: • Other causes
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