18 results
diagnosis hepatology liver algorithm differential transaminitis abnormal chemistry injury nejm nonalcoholic nonalcoholicfattyliverdisease nonalcoholicsteatohepatitis pathophysiology progression rheumatology tests activity alkphos antimda5
Histologic Features and Prevalence of Nonalcoholic Steatohepatitis (NASH). NASH is a potentially progressive type of nonalcoholic
Steatohepatitis (NASH ... NASH is a potentially ... liver disease (NAFLD ... specimens: ballooned hepatocytes ... #NAFLD #NonAlcoholicSteatoHepatitis
NAFLD / NASH Progression Timeline Healthy Liver → NAFLD/NASH → 0.25-3.2%/year → Cirrhotic NASH → 0.3-2.6%/year →
NAFLD / NASH Progression ... Healthy Liver → NAFLD ... /NASH → 0.25-3.2% ... /year → HCC • NAFLD ... Polymorphisms, Age #NAFLD
Pathogenesis of Nonalcoholic Steatohepatitis. Various factors, including inflammation, hyperinsulinemia or insulin resistance, and altered lipid homeostasis,
develop in fatty hepatocytes ... Pathophysiology #GI #IM #NASH ... #NAFLD #NonAlcoholicSteatoHepatitis
NAFLD Activity Score (NAS) 0–3 for steatosis 0–3 for inflammation 0–2 for ballooning hepatocytes NAS ≥5 is classified as definitive
NAFLD Activity Score ... (NAS) 0–3 for steatosis ... for ballooning hepatocytes ... as definitive NASH ... .2020.603926 #NAFLD
Assessment of Nonalcoholic Steatohepatitis (NASH) Severity in Patients With Nonalcoholic Fatty #Diagnosis #Pathology #NAFLD #NASH #Fibrosis #Staging
Steatohepatitis (NASH ... Diagnosis #Pathology #NAFLD ... #NASH #Fibrosis
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism AST and ALT: • AST: liver
Synthesis: in hepatocyte ... accumulation in hepatocyte ... conjugation in hepatocyte ... reuptake into hepatocyte ... Pathophysiology #Diagnosis #LFTs
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Function Tests (LFTs ... 100-500): • NAFLD ... Function #Tests #LFTs
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Hemochromatosis • NAFLD ... ALT < 5x ULN • NAFLD ... • Others #LFTs
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Wilson's, HH, NAFLD ... 5x ULN - NAFLD ... Burak @kwburak #LFTs
NASH/NAFLD - Liver Biopsy Indications Algorithm #NASH #NAFLD #Liver #Biopsy #Indications #Algorithm #diagnosis #hepatology
NASH/NAFLD - Liver ... Algorithm #NASH ... #NAFLD #Liver #
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