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Histologic Features and Prevalence of Nonalcoholic Steatohepatitis (NASH). NASH is a potentially progressive type of nonalcoholic
Steatohepatitis (NASH ... NASH is a potentially ... liver disease (NAFLD ... specimens: ballooned hepatocytes ... #NAFLD #NonAlcoholicSteatoHepatitis
NAFLD / NASH Progression Timeline Healthy Liver → NAFLD/NASH → 0.25-3.2%/year → Cirrhotic NASH → 0.3-2.6%/year →
NAFLD / NASH Progression ... Healthy Liver → NAFLD ... /NASH → 0.25-3.2% ... /year → HCC • NAFLD ... Polymorphisms, Age #NAFLD
Pathogenesis of Nonalcoholic Steatohepatitis. Various factors, including inflammation, hyperinsulinemia or insulin resistance, and altered lipid homeostasis,
develop in fatty hepatocytes ... Pathophysiology #GI #IM #NASH ... #NAFLD #NonAlcoholicSteatoHepatitis
NAFLD Activity Score (NAS) 0–3 for steatosis 0–3 for inflammation 0–2 for ballooning hepatocytes NAS ≥5 is classified as definitive
NAFLD Activity Score ... (NAS) 0–3 for steatosis ... for ballooning hepatocytes ... as definitive NASH ... .2020.603926 #NAFLD
Assessment of Nonalcoholic Steatohepatitis (NASH) Severity in Patients With Nonalcoholic Fatty #Diagnosis #Pathology #NAFLD #NASH #Fibrosis #Staging
Steatohepatitis (NASH ... Diagnosis #Pathology #NAFLD ... #NASH #Fibrosis
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Hemochromatosis • NAFLD ... ALT < 5x ULN • NAFLD ... Diagnosis #Algorithm #Causes
Causes of Hyperferritinemia - Differential Diagnosis Ferritin > 1000 Ferritin is the storage form of iron. Increased hepcidin
Causes of Hyperferritinemia ... leaving enterocytes, hepatocytes ... Most Common Causes ... 1% Most Common Causes ... is an uncommon cause
NASH/NAFLD - Liver Biopsy Indications Algorithm #NASH #NAFLD #Liver #Biopsy #Indications #Algorithm #diagnosis #hepatology
NASH/NAFLD - Liver ... Algorithm #NASH ... #NAFLD #Liver #
Childhood Immunization Schedule: Why we immunize • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
URT inflammation causes ... severe swelling causes ... severe swelling causes ... & hemorrhagic rash ... Vesicular & pruritic rash
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... Antitrypsin • Other: NAFLD ... Differential #Diagnosis #Causes
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