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Histologic Features and Prevalence of Nonalcoholic Steatohepatitis (NASH). NASH is a potentially progressive type of nonalcoholic
Steatohepatitis (NASH ... NASH is a potentially ... specimens: ballooned hepatocytes ... distribution of NASH ... #Epidemiology #NASH
Pathogenesis of Nonalcoholic Steatohepatitis. Various factors, including inflammation, hyperinsulinemia or insulin resistance, and altered lipid homeostasis,
develop in fatty hepatocytes ... Pathophysiology #GI #IM #NASH
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism AST and ALT: • AST: liver
Synthesis: in hepatocyte ... accumulation in hepatocyte ... from albumin upon hepatocyte ... conjugation in hepatocyte ... reuptake into hepatocyte
Pathology - Hepatocyte Pigments Lipofuschin (H&E) Alpha-I-antitrypsin globules (PAS-D) Mallory's hyaline / Mallory Denk Bodies Giant Mitochondria
Pathology - Hepatocyte ... bilirubinostasis (H&E) #Hepatocyte
The Mechanism of Small Interfering RNA (siRNA) Therapy. Synthetic double-stranded RNA containing an ALAS1-specific sequence is
exclusively on hepatocytes ... Within the hepatocyte
Excoriated papules with honey-colored crusting were present on the abdomen, back (Panel A), arms, and legs.
#Clinical #Derm ... Scabies #Microscopy #Rash
Crusted Scabies - Physical examination now revealed a generalized erythematous and scaly rash with intense hyperkeratotic
erythematous and scaly rash ... C) #Clinical #Derm
NAFLD Activity Score (NAS) 0–3 for steatosis 0–3 for inflammation 0–2 for ballooning hepatocytes NAS ≥5 is classified as definitive
Activity Score (NAS ... for ballooning hepatocytes ... NAS ≥5 is classified ... as definitive NASH ... Activity #Score #NAS
Strongyloides stercoralis Hyperinfection - Physical examination revealed reticulated purpuric patches with dusky centers on the abdomen,
biopsy of the rash ... #Clinical #Derm ... InfectiousDisease #Rash
Nikolsky’s Sign - Febrile & Positive Nikolsky’s Sign: Patients in this group have the potential to
sick (Fever + Rash ... Clinical #EM #IM #Derm
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