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differential algorithm management causes clinical cardiology radiology pulmonary pocus table signs comparison symptoms neurology pathophysiology classification peds hematology nephrology pediatrics
NAFLD Activity Score (NAS) 0–3 for steatosis 0–3 for inflammation 0–2 for ballooning hepatocytes NAS ≥5 is classified as definitive
Activity Score (NAS ... for ballooning hepatocytes ... NAS ≥5 is classified ... as definitive NASH ... #diagnosis #hepatology
Histologic Features and Prevalence of Nonalcoholic Steatohepatitis (NASH). NASH is a potentially progressive type of nonalcoholic
Steatohepatitis (NASH ... NASH is a potentially ... specimens: ballooned hepatocytes ... distribution of NASH ... #Epidemiology #NASH
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism AST and ALT: • AST: liver
Synthesis: in hepatocyte ... accumulation in hepatocyte ... conjugation in hepatocyte ... reuptake into hepatocyte ... Pathophysiology #Diagnosis
Pathogenesis of Nonalcoholic Steatohepatitis. Various factors, including inflammation, hyperinsulinemia or insulin resistance, and altered lipid homeostasis,
develop in fatty hepatocytes ... Pathophysiology #GI #IM #NASH
Pathology - Hepatocyte Pigments Lipofuschin (H&E) Alpha-I-antitrypsin globules (PAS-D) Mallory's hyaline / Mallory Denk Bodies Giant Mitochondria
Pathology - Hepatocyte ... bilirubinostasis (H&E) #Hepatocyte
The Mechanism of Small Interfering RNA (siRNA) Therapy. Synthetic double-stranded RNA containing an ALAS1-specific sequence is
exclusively on hepatocytes ... Within the hepatocyte
Assessment of Nonalcoholic Steatohepatitis (NASH) Severity in Patients With Nonalcoholic Fatty #Diagnosis #Pathology #NAFLD #NASH #Fibrosis #Staging
Steatohepatitis (NASH ... Nonalcoholic Fatty #Diagnosis ... Pathology #NAFLD #NASH
NAFLD / NASH Progression Timeline Healthy Liver → NAFLD/NASH → 0.25-3.2%/year → Cirrhotic NASH → 0.3-2.6%/year →
NAFLD / NASH Progression ... Liver → NAFLD/NASH ... year → Cirrhotic NASH ... → HCC • NAFLD/NASH ... → Cirrhotic NASH
Rash Morphology Description Algorithm #Rash #Morphology #Description #Algorithm #Skin #Dermatology #Diagnosis
Rash Morphology ... Algorithm #Rash ... #Dermatology #Diagnosis
Palpable Rash Algorithm #Palpable #Rash #Algorithm #Diagnosis #Skin #Dermatology #Differential
Palpable Rash Algorithm ... #Palpable #Rash ... #Algorithm #Diagnosis
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