411 results
The Mechanism of Small Interfering RNA (siRNA) Therapy. Synthetic double-stranded RNA containing an ALAS1-specific sequence is
exclusively on hepatocytes ... Within the hepatocyte ... #Pathophys #Honc ... siRNA #Therapy #NEJM
Early Events in Acute GVHD #Pathophys #Honc #GVHD #GraftVersusHostDisease #NEJM
GVHD #Pathophys #Honc ... GraftVersusHostDisease #NEJM
Possible Mechanisms Underlying Immune-Related Adverse Events #Pathophys #Honc #ImmuneRelatedAdverseEvents #Immunotherapy #NEJM
Events #Pathophys #Honc ... Immunotherapy #NEJM
The Pathway of Heme Synthesis, Showing Pathway Intermediates and End-Product Regulation by Heme #Pathophys #Honc #Heme
Heme #Pathophys #Honc ... Synthesis #Porphyria #NEJM
Biologic Events Leading to Chronic GVHD #Pathophys #Honc #Pharm #GVHD #GraftVersusHostDisease #Therapeutic #Pathways #NEJM
GVHD #Pathophys #Honc ... Therapeutic #Pathways #NEJM
Role of G6PD in Protection against Oxidative Damage #Pathophys #Peds #Genetics #Honc #Favism #g6pd #NEJM
Peds #Genetics #Honc ... #Favism #g6pd #NEJM
An AAV5 vector with a functional factor VIII gene tested in men with hemophilia A #EBM
hemophilia A #EBM #Honc ... VisualAbstract #NEJM
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
Synthesis: in hepatocyte ... accumulation in hepatocyte ... from albumin upon hepatocyte ... conjugation in hepatocyte ... reuptake into hepatocyte
Signaling Mechanism of PD-1 and PD-L1 and Inhibition of PD-1 Signaling in Microsatellite-Instability–High Cancers. MHC1 denotes
Pathophysiology #Honc ... MicrosatelliteInstability #NEJM
Pathogenesis of Nonalcoholic Steatohepatitis. Various factors, including inflammation, hyperinsulinemia or insulin resistance, and altered lipid homeostasis,
develop in fatty hepatocytes ... NonAlcoholicFattyLiverDisease #NEJM