34 results
The Mechanism of Small Interfering RNA (siRNA) Therapy. Synthetic double-stranded RNA containing an ALAS1-specific sequence is
exclusively on hepatocytes ... Within the hepatocyte ... #Pathophys #Honc
Catecholamine Vasopressor Effect Sites and Indications #Pathophys #Management #EM #IM #PCC #Catecholamine #Comparison #Table #Epi #Norepi
and Indications #Pathophys ... Catecholamine #Comparison #Table
Pathogenesis of Nonalcoholic Steatohepatitis. Various factors, including inflammation, hyperinsulinemia or insulin resistance, and altered lipid homeostasis,
develop in fatty hepatocytes ... Pathophysiology #GI
N-Acetyl Cysteine (NAC) Therapy Mechanism of Action: The non-toxic route of APAP metabolism gets saturated in
the extent of hepatocyte ... #Pathophys #Toxicology
Differential Diagnosis in Upper and Lower GI Bleed
 
- By Dr. Eric Strong @DrEricStrong 

#Upper #Lower
Upper and Lower GI ... Differential #Diagnosis #Table
Differential Diagnosis of Jaundice, Presentation Pattern #Diagnosis #EM #IM #GI #Jaundice #Pattern #LFTs #Workup #Table #Differential
Diagnosis #EM #IM #GI ... #LFTs #Workup #Table
Causes of ileitis beyond Crohn’s disease and infections include systemic disorders -spondyloarthropathies, vasculitides, ischemia, and amyloidosis
See below for table ... complements of our GI ... PMC2914216/ #Diagnosis #GI ... #Differential #Table
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
Mechanism Decreased GI ... hypomagnesemia Excessive GI ... Low #Magnesium #Table
Causes of Hyperferritinemia - Differential Diagnosis
Ferritin > 1000
Ferritin is the storage form of iron. Increased hepcidin
leaving enterocytes, hepatocytes ... cause increased GI
Shock - Differential Diagnosis by Classification

Hypovolemic (Intravascular volume depletion)
 - Hemorrhagic 
   • Trauma
Trauma • GI ... Classification #Table