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SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
SAPHO syndrome is ... Skin findings: Hidradenitis ... affected areas and if negative ... and lower jaw Treatment ... osteoarticular and skin disease
Causes of Culture Negative Abscess - Differential Diagnosis Framework Consider prior antibiotics as a cause of a
Causes of Culture Negative ... SAPHO, Sweet's Syndrome ... , hidradenitis suppurativa ... Autoimmune: Crohn's disease ... Auto-Inflammatory: SAPHO syndrome
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
BEE Syndromes - ... and less common diseases ... diagnosis and treatment ... Vogt-Koyanagi-Harada (VKH) disease ... polychondritis • Behcet disease
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal Syndrome ... Pulmonary Renal Syndromes ... polyangiitis) - ANCA-negative ... vasculitis, Behcet disease ... Goodpasture's Disease
Behcet's Syndrome - Treatment Ulcers: • Treatment: Topical steroids • Prevention: Colchicine • Azathioprine for refractory disease Arthritis:
Behcet's Syndrome ... - Treatment Ulcers ... : • Treatment: ... for refractory disease ... #Syndrome #Treatment
Commonly Used Diagnostic Tests for Celiac Disease Tissue transglutaminase (tTG) IgA antibodies - Most reliable noninvasive test
Tests for Celiac Disease ... specificity - Falsely negative ... ) - May be negative ... HLA-DQ8 - High negative ... Reflects response to treatment
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
ULN R - Renal disease ... Causes of false- negative ... chain deposition disease ... plasmacytoma, POEMs syndrome ... and autoimmune diseases
Korsakoff Syndrome Clinical Findings: • Confabulation: Usually initial phase of the disease • Anterograde amnesia: Memory impairment
Korsakoff Syndrome ... initial phase of the disease ... Therefore, Korsakoff Syndrome ... Encephalopathy Treatment ... neudrawlogy #Korsakoff #Syndrome
Carpal Tunnel Syndrome Compression of median nerve Risk Factors • Obesity • Female gender
Carpal Tunnel Syndrome ... connective tissue diseases ... Aromatase inhibitor Treatment ... #CarpalTunnel #Syndrome
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
with more severe disease ... Used to monitor disease ... block • Sjogren syndrome ... polymyositis overlap syndrome ... Treatment: •
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