22 results
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
imaging: Hepatic ... extensive necrosis and hemorrhage ... often <5 mg/dL, higher ... obstetrics #hepatitis #comparison ... #differential #
Appearance of Liver Lesions on Various Imaging Modalities
 • Computed Tomography (CT) - Arterial Phase, Portal
Appearance of Liver ... , Metastasis #Liver ... #Lesions #Hepatic ... POCUS #radiology #differential ... #diagnosis #comparison
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Differential Diagnosis ... Pre-analytical cause (e.g. heparin ... thrombin inhibitors, heparin ... • Reduced liver ... • Massive hemorrhage
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Early liver disease ... unfractionated heparin ... Reduced liver synthesis ... Massive hemorrhage ... Causes #diagnosis #differential
Portal venous gas on hepatic ultrasound: A concerning finding in the critically ill patient that should
venous gas on hepatic ... ultrasound: A concerning ... reflection on the differential ... of air in the hepatic ... #hepatology #liver
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
ALP) Elevation - Differential ... disturbance (obstructed liver ... phosphatase sources: - Highest ... • Bone • Liver ... elevation DDX of Hepatic
Appearance of Liver Lesions on Computed Tomography (CT) - Arterial Phase, Portal Venous Phase and Delayed
Appearance of Liver ... , Metastasis #Liver ... #Lesions #Hepatic ... CT #radiology #differential ... #diagnosis #comparison
Ruptured Tubal Ectopic Pregnancy on Pelvic Ultrasound

Young female.  Lower abdominal pain/VB.  UCG pos. Soft
Pregnancy on Pelvic Ultrasound ... Diagnosis/differential ... Answer: Pt has IUD ... assume that acute hemorrhage ... Pregnancy #Pelvis #Ultrasound
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• Prolonged PT ... Acral cyanosis • Hemorrhagic ... Fibrinogen: ↓ • PT ... DIC • Severe Liver ... 100mg/dL) - Heparin
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Liver Chemistries ... Identify Acute Liver ... Coagulation factors: PT ... replaced by non-hepatic ... chemistry #diagnosis #differential