7 results
Signet ring cell histiocytes in lymph node sinuses! This can mimic metastatic adenocarcinoma. Histiocytes have ingested
Signet ring cell histiocytes ... Histiocytes have ... SignetRing #Cell #Histiocytes
Physical examination revealed extensive umbilicated papules (Panel A). A biopsy specimen obtained from a papule showed
structures in histiocytes
Hemophagocytic Lymphohistiocytosis (HLH)
Clinical Features: Fever, Splenomegaly, Hepatomegaly, Lymphadenopathy, Confusion
Classic lab findings in HLH: ↑↑ ferritin, Anemia,
Criteria for HLH (The Histiocyte
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Causes: Cancer, Histiocytic
Anaplastic large cell lymphoma, ALK+
Clinical
 • First 3 decades of life, M>F
 • Often nodal +
mixed w reactive histiocytes
Langerhans Cell Histiocytosis (LCH)

Granulomatous Lesions comprising langerin-positive histiocytes and an inflammatory infiltrate can arise in virtually
langerin-positive histiocytes ... • Part of the histiocytic ... • Large pale histiocytes
Babesiosis on Peripheral Smear
85 M from SE USA, hx splenectomy, IgG4 plasmacytic syndrome: F, chills, profound
smear shown: no shistocytes