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Algorithm for the Evaluation and Management of Sickle Cell Crises
Clinical Manifestations and Management

#Diagnosis #Management #Hematology #SickleCell
of Sickle Cell Crises ... Management #Diagnosis ... #Management #Hematology
Systemic Sclerosis (Scleroderma)
Limited - CREST:
 • Calcinosis
 • Raynaud phenomenon
 • Esophageal dysmotility
 • Sclerodactyly
 •
Scleroderma renal crisis ... #Scleroderma #diagnosis ... signs #symptoms #rheumatology
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
sickle cell hepatic crisis ... treatment of SCD crisis ... Hepatobiliary #hepatology ... #differential #diagnosis
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
Differential diagnosis ... Scleroderma renal crisis ... #differential #diagnosis ... #hematology #hemolysis
Malignant Hyperthermia Crisis - Guidelines for Crises in Anaesthesia
Unexplained increase in ETCO2 AND tachycardia AND increased
Malignant Hyperthermia Crisis ... Guidelines for Crises ... Guidelines for crises ... Anesthesiology #Anesthesia #Intraoperative ... #Checklist #Diagnosis
Intraoperative Tachycardia - Guidelines for Crises in Anaesthesia
Tachycardia in theatre is often due to inadequate depth
Intraoperative Tachycardia ... Guidelines for Crises ... Guidelines for crises ... Anesthesiology #Anesthesia #Intraoperative ... #Checklist #Diagnosis
Chondrodermatitis nodularis 
 - Scaly papule on ear, usually helix 
 - Painful, especially when sleeping
sleeping - Probably arises ... Chondrodermatitis #Nodularis #Dermatology ... #Diagnosis #Benign
Intraoperative Massive Blood Loss - Guidelines for Crises in Anaesthesia
Expected or unexpected major haemorrhage

❶ Call for
Intraoperative Massive ... Guidelines for Crises ... Guidelines for crises ... Anesthesiology #Anesthesia #Intraoperative ... #Checklist #Diagnosis
Systemic Sclerosis Associated Autoantibodies
Anti-topoisomerase I (anti-Sc170): Diffuse skin disease, Pulmonary fibrosis
Anti-centromere: Limited skin disease (~93-95%), Pulmonary
Diffuse, Renal crisis ... Autoantibodies #diagnosis ... #rheumatology
Intraoperative Bronchospasm - Guidelines for Crises in Anaesthesia

❶ Call for help and inform theatre team of
Intraoperative Bronchospasm ... Guidelines for Crises ... Consider alternate diagnoses ... Guidelines for crises ... #Checklist #Diagnosis