169 results
Acromegalic Hand: Markedly enlarged hand resulting from excess growth hormone. For reference
purposes, the comparison hand is
Acromegalic Hand ... excess growth hormone ... Clinical #Photo #Acromegaly ... #Acromegalic #Hand
Acromegaly 
Caused by over-secretion of growth hormone (GH) from the pituitary gland. 
The condition is rare
Acromegaly Caused ... over-secretion of growth hormone ... #Acromegaly #Signs
Acromegaly: Facial changes secondary to elevated growth hormone levels. Note in particular 
prominent supra-orbital ridge, jaw,
Acromegaly: Facial ... elevated growth hormone ... Clinical #Photo #Acromegaly
Acromegaly 2: Facial changes secondary to elevated growth hormone levels. Note in particular 
prominent supra-orbital ridge,
Acromegaly 2: Facial ... elevated growth hormone ... Clinical #Photo #Acromegaly
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
Growth Hormone Excess ... clinical findings • Acromegaly ... plate fusion -> acromegaly ... rare causes of acromegaly
Clinical Effects of Large and Small Pituitary Tumours
Local complications - Headache, Visual field defect, Disconnection hyperprolactinaemia,
pituitary apoplexy) Hormone ... Hypogonadism • Acromegaly ... Hypopituitarism • Growth hormone
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Feedback Loop: Growth Hormone ... (GH) Growth Hormone ... - Giantism or acromegaly
Acromegaly Testing Algorithm
INDICATIONS FOR TESTING:
 • Adults – enlarged facial or acral features, abnormal musculoskeletal growth
Acromegaly Testing ... load • Growth Hormone ... ARUPConsult @ARUPLabs #Acromegaly
Hormonal Regulation at Various Parts of the Menstrual Cycle
#Pathophysiology #Endocrinology #Hormones #Menstrual #Cycle #Regulation #Hormonal
Hormonal Regulation ... Endocrinology #Hormones ... Cycle #Regulation #Hormonal
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
bruit or signs of hormonal ... Cushing's syndrome, Acromegaly