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bruising hemolytic oncology purpura rash rheumatology thrombocytopenia algorithm bleeding gpa granulomatosis hemolysis hemostasis lymphoma management mds myelodysplasia myelodysplastic nonpalpable palpable
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
vs Extravascular ... Causes Intravascular ... hemoglobinuria (PNH) Extravascular ... #Causes #differential ... #diagnosis #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... - Hemolytic anemia ... #Diagnosis #hematology ... #nonpalpable #dermatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
and Platelet Disorders ... Diagnosis and Workup ... or if a primary hematologic ... #Disorders #Differential ... #Workup #hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... IVIG infusion Intravascular ... : TTP, HUS, DIC, ... Diagnosis #causes ... #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... reflection of intravascular ... hemolysis Platelet ... WBC count and differential ... #Workup #Hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... Lymphoma Workup ... - Low Hb and platelets ... Immunohistochemical studies (to differentiate ... #hematology #oncology
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
Causes of Purpura ... Immune - ITP ... (disseminated intravascular ... peds #pediatrics #diagnosis ... #differential #
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... GPA causes disease ... Necrotising vasculitis, extravascular ... vasculitis #Dermatologic ... Polyangiitis #GPA #dermatology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Thrombocytopenia - Abnormal platelet ... Vasculitis - Collagen disorders ... fulminans - DIC - TTP ... deficiency Work ... #Causes #dermatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... Workup: • Complete ... blood count with differential ... #diagnosis #hematology
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