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diagnosis hematology monoclonal mgus classification significance acute agglutinin aki cancer clinical cold gap globulin hemolytic hodgkins injury kidney lymphoma management
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
and Monoclonal Gammopathies ... C - HyperCalcemia ... 40 ml/min A - Anemia ... MGUS #diagnosis #hematology ... #oncology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Significance (MGUS) - Differential ... Ig deposition disease ... Significance #MGUS #Differential ... #Diagnosis #hematology ... #oncology
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
Cancer Related • Hypercalcemia ... LC deposition disease ... • Monoclonal gammopathy ... #AKI #Cancer #Oncology ... #Differential #
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
Monoclonal Gammopathy ... No evidence of anemia ... damage, such as hyperCalcemia ... insufficiency, Anemia ... #diagnosis #oncology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
• Symptoms of anemia ... • hemolytic anemia ... younger pts) Differential ... IgM monoclonal gammopathy ... #hematology #diagnosis
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... (-) hemolytic anemia ... Sneddon-Wilkinson disease ... #Monoclonal #Differential ... #Diagnosis #Oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... Immunohistochemical studies (to differentiate ... number of sites of disease ... #oncology #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
• Aplastic Anemia ... Myeloproliferative Disease ... blood count with differential ... Syndromes #diagnosis #hematology ... #oncology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
• Heavy chain disease ... plasmacytoma • Castleman disease ... Sarcoidosis) • Liver disease ... Thalassemia, Sickle cell anemia ... Gap #ProteinGap #differential
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