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Causes of Hypercalcemia

#Differential #Hypercalcemia #Diagnosis #Causes #Endocrinology
Causes of Hypercalcemia ... #Differential ... #Hypercalcemia ... #Diagnosis #Causes ... #Endocrinology
Causes of Hypercalcemia
Hypercalcemia due to increased bone Ca2+ resorption:
 • Primary hyperparathyroidism, Malignancy, Pseudohyperparathyroidism, Renal failure,
Causes of Hypercalcemia ... Hypercalcemia ... #Causes #differential ... #diagnosis #calcium ... #high #endocrinology
Causes of Hypercalcemia - Differential Diagnosis Algorithm
 • Primary Hyperparathyroidism 
 • Possible Familial Hypocalciuric Hypercalcemia
Causes of Hypercalcemia ... Hypocalciuric Hypercalcemia ... • Humoral Hypercalcemia ... DTomacruzM #Hypercalcemia ... #Causes #endocrinology
Hypercalcemia - Differential Diagnosis Algorithm
Elevated PTH (High or normal):
 • Primary Hyperparathyroidism
 • Familial Hypocalciuric Hypercalcemia
Low
Hypercalcemia - ... Differential Diagnosis ... Hypocalciuric Hypercalcemia ... Thiazides/Lithium #Hypercalcemia ... #causes #endocrinology
Hypercalcemia Workup and Differential Diagnosis Framework
1) Determine whether PTH-dependent
2) Assess for other hormonal causes
3) Assess for
Hypercalcemia Workup ... and Differential ... Diagnosis Framework ... uw_IMresidency #Hypercalcemia ... #endocrinology
Hypercalcemia - EKG Findings
Causes of Hypercalcemia 
• Malignancy 
• Milk-alkali syndrome 
• Vitamin D toxicity 
•
Hypercalcemia - ... of Hypercalcemia ... Thiazide diuretics #Hypercalcemia ... #Causes #Diagnosis ... #Cardiology
Hypomagnesemia - Differential Diagnosis
Renal Causes of Hypomagnesemia - Familial:
Bartter syndrome and Gitelman syndrome, Isolated recessive hypomagnesemia,
Hypomagnesemia - Differential ... Diagnosis Renal ... pentamidine), Hypercalcemia ... #diagnosis #causes ... nephrology #magnesium #low
The Diagnostic Approach to Hyperkalemia
Drugs
 - Amiloride
 - Spironolactone
 - Triamterene
 - Trimethoprim
 - Pentamidine
 -
The Diagnostic Approach ... to Hyperkalemia ... Beta-Blockers #Hyperkalemia ... #differential # ... causes
Adrenal Insufficiency Differential Diagnosis Algorithm
Clinical suspicion: Weakness, fatigue, nausea, musculoskeletal pain, dizziness, volume depletion, abdominal pain,
Diagnosis Algorithm ... Clinical suspicion ... Weakness, fatigue, nausea ... hyponatremia, hyperkalemia ... #endocrinology
Hypercalcemia Evaluation
1) Clinical clues
 - Is the patient symptomatic?
 - Family history?
 - Have you done
Hypercalcemia Evaluation ... 1) Clinical clues ... FeCa <1 %) - Low ... BrighamChiefs #Hypercalcemia ... #diagnosis #endocrinology