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diagnosis nephrology management causes classification medications table acute agents aki binders binding cardiology chemotherapy comparison complexes disorders diuresis diuretics electrolytes
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
Agents to Treat Hyperkalemia ... to moderate); hypokalemia ... ; hypokalemia; constipation ... disturbances (including hypokalemia ... #Binding #Hyperkalemia
Cancer agents and Electrolyte Disorders • Hypocalcemia: Cisplatin from Low Mg, Cetuximab- due to low Mg Axitinib,
Cancer agents and ... Disorders • Hypocalcemia ... Regorafenib • Hypomaqnesemia ... Trastuzumab • Hypokalemia ... chemotherapy #diagnosis #differential
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
• LDH ↑ • Hyperkalemia ... Hyperphosphatemia • Hypocalcemia ... /Late - Hypercalcemia ... Monitor potassium ... Dialysis for severe hyperkalemia
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
Patients with Cancer ... Cancer Related ... • Hypercalcemia ... malignancies Treatment ... #Oncology #Differential
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Family history of hypokalemia ... • Unexplained hypokalemia ... pressure Labs: • Hypokalemia ... ratio 0.5%) Differential ... pathophysiology #Hypokalemia
Premature Ventricular Complexes (PVC's) - Summary Framework Why PVCs? Can be the first manifestation of cardiac
Inherited arrhythmia syndromes ... (e.g., long QT syndrome ... Sympathomimetics • Hypomagnesemia ... • Hypokalemia ... more intensive treatment
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Autoimmune disease, Cancer ... Blood transfusion, Hypercalcemia ... Reversible course Differential ... epilepticus Treatment ... underlying cause • Treatment
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
disequilibrium syndrome ... Loop Diuretics; High-Ceiling ... Hyponatremia • Hypercalcemia ... Tolvaptan) • Treatment ... Diuresis #Nephrology #Pharmacology
Causes of Hyperkalemia l. Pseudohyperkalemia A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis B.
Causes of Hyperkalemia ... axis; T risk of hyperkalemia ... #Hyperkalemia ... #Differential # ... Diagnosis #High
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