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diagnosis causes nephrology oncology rhabdomyolysis tumor acute aki cancer gitelman hematology hypokalemia injury kidney leukostasis pathophysiology summary tumorlysis uricacid
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS Laboratory TLS: • Uric
Tumor Lysis Syndrome ... (TLS) and Treatment ... other symptomatic hypocalcemia ... hydroxide • Hyperkalemia ... • Hypocalcemia
Tumor Lysis Syndrome An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... 6L/day) • For hyperkalemia ... otherwise treat with "hyperkalemia ... #Syndrome #TLS ... #oncology #management
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
immature blasts and high ... hydration - Hyperkalemia ... #Syndrome #TLS ... #diagnosis #management ... #hematology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
• LDH ↑ • Hyperkalemia ... Hyperphosphatemia • Hypocalcemia ... /Late - Hypercalcemia ... Monitor potassium ... Dialysis for severe hyperkalemia
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
Cancer Related • Hypercalcemia ... malignancies Treatment ... Interleukin-2) • Tumor lysis ... Cancer #Oncology #Differential ... #Diagnosis #Classification
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Family history of hypokalemia ... • Unexplained hypokalemia ... pressure Labs: • Hypokalemia ... ratio 0.5%) Differential ... pathophysiology #Hypokalemia
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
Rhabdomyolysis - Differential ... Diagnosis and Management ... HIV, Influenza, TSS ... Monitor potassium ... Dialysis for severe hyperkalemia
Causes of Hyperkalemia l. Pseudohyperkalemia A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis B.
Causes of Hyperkalemia ... Rapid tumor lysis ... axis; T risk of hyperkalemia ... #Hyperkalemia ... #Potassium #Classification
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