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diagnosis causes algorithm hematology nephrology blood lowcalcium lysis neurology oncology product reactions rhabdomyolysis table tumor calcium cardiology complexes deficiency diuresis
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS Laboratory TLS: • Uric
(TLS) and Treatment ... other symptomatic hypocalcemia ... Treatment of TLS ... hydroxide • Hyperkalemia ... • Hypocalcemia
Reflex Testing - Causes of Hyporeflexia and Hyperreflexia Focal Hyporeflexia: • Radiculopathy, Mononeuropathy, Polyneuropathy, Acute stroke,
Hyporeflexia: • Hypercalcemia ... , Hypermagnesemia ... Hyperreflexia: • Hypocalcemia ... , Hypomagnesemia ... Testing #Causes #differential
Causes of Hypercalcemia Hypercalcemia due to increased bone Ca2+ resorption: • Primary hyperparathyroidism, Malignancy, Pseudohyperparathyroidism, Renal failure,
Causes of Hypercalcemia ... Hypercalcemia ... Immobilization Hypercalcemia ... hypocalciuria, Thiazides Hypercalcemia ... intoxication #Hypercalcemia
Hypocalcemia - Differential Diagnosis Algorithm - Low and High Phosphate LOW PHOSPHATE - Low/NormaI PTH
Hypocalcemia - Differential ... Phenytoin, Nephrotic Syndrome ... Poisoning #Hypocalcemia ... #Differential # ... Algorithm #Phosphate #endocrinology
Hypocalcemia - Differential Diagnosis Algorithm - Low and High PTH LOW PTH - Hypoparathyroid - Congenital (Pediatric)
Hypocalcemia - Differential ... polyendocrinopathy • Hypomagnesemia ... Tumor lysis syndrome ... laxatives) #Hypocalcemia ... Algorithm #PTH #endocrinology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
• LDH ↑ • Hyperkalemia ... Hyperphosphatemia • Hypocalcemia ... /Late - Hypercalcemia ... Monitor potassium ... Dialysis for severe hyperkalemia
Tumor Lysis Syndrome An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... 6L/day) • For hyperkalemia ... otherwise treat with "hyperkalemia ... #TLS #oncology ... #management #UricAcid
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
immature blasts and high ... Spontaneous if high ... hydration - Hyperkalemia ... #TLS #diagnosis ... #management #hematology
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Family history of hypokalemia ... • Unexplained hypokalemia ... pressure Labs: • Hypokalemia ... ratio 0.5%) Differential ... pathophysiology #Hypokalemia
Clinical Feature of Hypomagnesemia and Magnesium Deficiency • Electrolyte Disturbance: Hypokalemia, Hypocalcemia • Neuromuscular and central
Electrolyte Disturbance: Hypokalemia ... , Hypocalcemia ... Chronic fatigue syndrome ... signs #symptoms #Treatment ... #management #Magnesium
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