12 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Relevant HES Variants ... disorders • Diagnosis ... #Syndrome #HES ... #Hematology #eosinophilia ... #eosinophils #diagnosis
Hypereosinophilia Syndrome (HES) - Diagnosis and Management
Definition: An absolute eosinophil count (AEC) greater than 1500 and
Syndrome (HES) ... with blood eosinophilia ... #Syndrome #HES ... #eosinophilia #diagnosis ... #hematology #differential
Approach to Eosinophilic Lung Diseases
 • Acute Eosinophilic Pneumonia (< 1 wk) - ~30yo, M; Recent
Approach to Eosinophilic ... • Acute Eosinophilic ... Syndrome (> 6 mo ... loss; CV, CNS, skin ... #table #eosinophilia
Eosinophilic Gastroenteritis: Treatment Options Based on Severity of the Disease
Mild:
 • Trial of PPI
 • Trial
Eosinophilic Gastroenteritis ... Severity of the Disease ... : • Hematology ... • Additional diagnostic ... scan #EoE #Eosinophilic
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Amyloidosis • Eosinophilic ... Antiphospholipid-antibody syndrome ... Sarcoidosis #dermatology ... #joint #pain #skin ... #differential #diagnosis
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Pulmonary ... Spondyloarthropathies, SLE • Pulmonary ... Scleroderma Thickened skin ... Amyloidosis • Eosinophilic ... #differential #diagnosis
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Alpha & Mu) Skin ... Scleromyxedema (CNS+GI+CVS+joints ... Episodic angioedema+eosinophilia ... Paraproteinemias #Hematology ... #Differential #Diagnosis
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
- Differential Diagnosis ... vesicular eruption • Joints ... progressive) EGPA (Eosinophilic ... Polyangiitis): • Eosinophilia ... Palpable purpura, joint
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... progressing GN • New pulmonary ... • EGPA: - Eosinophilia ... vesicular eruption - Joints ... • Cogan Syndrome
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
thrombophlebitis, pulmonary ... Cryofibrinogenemia Diagnosis ... Antiphospholipid syndrome ... Cryofibrinogenemia #diagnosis ... #rheumatology #hematology