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differential hematology eosinophilic oncology allergy cold compared disorders eoe eosinophil erythemas gastroenteritis leukemia lung management monoclonal paraproteinemias rheumatology scleroderma treatment
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... Peripheral blood eosinophilia ... symptoms (eg, skin ... #Differential #diagnosis ... #hematology #eosinophilia
Eosinophilia - Differential Diagnosis Algorithm Idiopathic Eosinophilia Primary Eosinophilia: • Primary hypereosinophilic syndrome • Eosinophilic Leukemia • MPN/MDS
Diagnosis Algorithm ... GI, lung, skin), ... AI: EGPA, IgG-4 disease ... , Behcet disease ... Chronic inflammatory disease
Approach to Eosinophilic Lung Diseases • Acute Eosinophilic Pneumonia (< 1 wk) - ~30yo, M; Recent
Lung Diseases ... • Acute Eosinophilic ... #Lung #Diseases ... #diagnosis #comparison ... #table #eosinophilia
Scleroderma Like Conditions - Differential Diagnosis Eosinophilic Fasciitis: - Orange peel induration (peau d'orange) of proximal extremities
Eosinophilic Fasciitis ... facei peripheral eosinophilia ... patients with kidney disease ... Graft-Versus-Host Disease ... #comparison #table
Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
the population Disease ... Autoimmune diseases ... Lymphoproliferative diseases ... Insect stings Disease ... neutrophils and eosinophils
Eosinophilic Gastroenteritis: Treatment Options Based on Severity of the Disease Mild: • Trial of PPI • Trial
Eosinophilic Gastroenteritis ... Severity of the Disease ... Concern for HES: • Hematology ... • Additional diagnostic ... scan #EoE #Eosinophilic
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... Sneddon-Wilkinson disease ... Episodic angioedema+eosinophilia ... Paraproteinemias #Hematology ... #Differential #Diagnosis
Erythemas Summarized Erythema ab igne • A dermatosis that results from repeated exposure to heat (fires, heating
early localized disease ... called "Bazin's disease ... so-called fifth disease ... shows numerous eosinophils ... #diagnosis #dermatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... • (Peripheral eosinophilia ... CLL -> Invade Skin ... #Leukemia #Hematology ... #Oncology #Diagnosis
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