35 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Hypereosinophilia ... disorders • Diagnosis ... Syndrome #HES #Hematology ... #eosinophilia # ... eosinophils #diagnosis
Causes of Eosinophilia - Differential Diagnosis
Bugs:
 - Fungus (aspergillosis)
 - Viral (HIV)
 - Ectoparasites (scabies, myiasis)
Causes of Eosinophilia ... DRESS - AIN - Eosinophilic ... Asthma Tugs (vasculitis ... coyefish379 #Eosinophilia ... #Causes #hematology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... Peripheral blood eosinophilia ... symptoms (eg, skin ... #Differential #diagnosis ... #hematology #eosinophilia
Hypereosinophilia Syndrome (HES) - Diagnosis and Management
Definition: An absolute eosinophil count (AEC) greater than 1500 and
Definition: An absolute eosinophil ... attributable to eosinophilia ... confirmed tissue eosinophilia ... with blood eosinophilia ... #diagnosis #hematology
Eosinophilia - Differential Diagnosis Algorithm
Idiopathic Eosinophilia
Primary Eosinophilia:
 • Primary hypereosinophilic syndrome
 • Eosinophilic Leukemia
 • MPN/MDS
Diagnosis Algorithm ... : • Primary hypereosinophilic ... GI, lung, skin), ... , Behcet disease ... #Differential #Diagnosis
Small Vessel Vasculitides
 • Granulomatosis with polyangiitis - Granulomatous manifestations (e.g., nasal crusting, destructive sinusitis, pulmonary
Interstitial lung disease ... • Eosinophilic ... polyangiitis - Asthma. eosinophilia ... in absence of skin ... #diagnosis
Approach to Eosinophilic Lung Diseases
 • Acute Eosinophilic Pneumonia (< 1 wk) - ~30yo, M; Recent
Approach to Eosinophilic ... • Acute Eosinophilic ... loss; CV, CNS, skin ... #pulmonary #differential ... #diagnosis #comparison
Categories of disease to consider for eosinophilic meningitis:
-Multicellular parasites (worms and flukes)
-Fungal: Cocci
-Atypical bacterial/mycobacterial: TB, syphilis,
to consider for eosinophilic ... Hypereosinophilic ... (sarcoid) -Vasculitis ... #Eosinophilic # ... Eosinophilia #Meningitis
Secondary Causes of Esophageal Eosinophilia (EoE) - Differential Diagnosis
 • Gastroesophageal reflux disease
 • Eosinophilic gastrointestinal
of Esophageal Eosinophilia ... • Eosinophilic ... Achalasia • Hypereosinophilic ... disorders • Vasculitis ... #esophagitis #Eosinophilic
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Amyloidosis • Eosinophilic ... Hypersensitivity vasculitis ... Antiphospholipid-antibody syndrome • Vasculitis ... Sarcoidosis #dermatology ... #differential #diagnosis