84 results
SEPSIS AND SEPTIC SHOCK

DEFINITION AND PATHOPHYSIOLOGY
 • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
• 49 million cases ... /hypofunction. ... COMMON CAUSES + ... CLINICAL RECOGNITION ... CLINICAL FEATURES
Causes, classification and compensatory responses to shock.

Shock can be caused by any pathological process that leads
Causes, classification ... Shock can be caused ... vasodilatation, myocardial dysfunction ... The cause of shock ... is often clinically
Anosmia / Smell Dysfunction - Differential Diagnosis Algorithm
Nasal Obstruction/ URTI:
 • Septal Deviation
 • Allergic Rhinitis
Anosmia / Smell Dysfunction ... Mellitus • Adrenal Hypofunction ... • Adrenal Hyperfunction ... Anosmia #Smelling #Dysfunction ... Diagnosis #Algorithm #Causes
Non-lschemic Causes of Cardiogenic Shock:

Beta-Blockers, Calcium Channel Blockers, Digoxin 

Myocarditis 

Cardiomyopathies (sarcoidosis, amyloidosis, Takatsubo, 
hemochromatosis) 

Valvular
Non-lschemic Causes ... of Cardiogenic Shock ... , Sinus nodal dysfunction ... #Nonlschemic #Causes ... #Cardiogenic #Shock
Tachypnea - Differential Diagnosis Framework

Definitions
 • Tachypnea: Respiratory rate > 20/min, shallow breathing in adults
 •
PVFM) Cardiac Causes ... Hematologic Causes ... • Hypovolemic shock ... Severe kidney dysfunction ... Nervous System Dysfunction
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
Shock Overview ... of hypotension Shock ... death -> end-organ dysfunction ... death Common Clinical ... #differential #causes
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
Shock Overview ... of hypotension Shock ... death -> end-organ dysfunction ... death Common Clinical ... #differential #causes
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... 64%) • Renal dysfunction ... (16%) • Shock ... Treat primary cause ... Coagulation #diagnosis #causes
Causes of Adrenal Insufficiency - Differential Diagnosis Algorithm
Autoimmune:
 • Isolated
 • Polyglandular autoimmune syndrome 1
 •
Causes of Adrenal ... Thrombophilia • Critical ... • Pituitary dysfunction ... • Hypothalamic dysfunction ... Diagnosis #Algorithm #Causes
Secondary Causes of Hypothermia - Differential Diagnosis Framework

Definition:
- Core temp < 35°C

Infectious:
 - Sepsis

Neuromuscular Disease:
 -
Secondary Causes ... - Hypothalamic dysfunction ... Multi-system trauma - Shock ... Diagnosis #Secondary #Causes