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SEPSIS AND SEPTIC SHOCK DEFINITION AND PATHOPHYSIOLOGY • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
monocyte dysfunction/hypofunction ... injury: Glycocalyx loss ... CLINICAL RECOGNITION ... CLINICAL FEATURES
Anosmia / Smell Dysfunction - Differential Diagnosis Algorithm Nasal Obstruction/ URTI: • Septal Deviation • Allergic Rhinitis
Mellitus • Adrenal Hypofunction ... • Adrenal Hyperfunction ... #Dysfunction #Loss
Cushing Syndrome Testing Algorithm INDICATIONS FOR TESTING: • Suspected Cushing syndrome (central obesity, muscle weakness, refractory hypertension) Testing:
endocrinology #Adrenal #Hyperfunction
Medications associated with neuroleptic malignant syndrome First-generation and second-generation antipsychotics are dopamine receptor antagonists, which produce a
of dopaminergic hypofunction
Principal patterns of loss of sensation. (a) Thalamic lesion: sensory loss throughout opposite side (rare).
Principal patterns of loss ... lesion: sensory loss ... and ipsilateral loss ... and temperature loss ... Comprehensive Review in Clinical
Black and Bloody Stools - Melena and Hematochezia Melena - Refers to passage of black, tarry (sticky
Involves loss ... Less commonly, when ... slow, blood loss ... or anus; much less ... stools; blood loss
Scleritis, Episcleritis Pearls -Scleritis is characterized by significant pain, pain with eye movement, vision loss, and vessels
movement, vision loss ... Episcleritis is typically less ... with no vision loss
Muehrcke's Lines (Leukonychia striata) Narrow while transverse lines (Not depressed, compared to Beau's lines). Usually 2 or
increase protein loss ... hypoalbunemia (usually less ... #PhysicalExam #Clinical
Stroke Evaluation and Management Algorithm Clinical suspicion of stroke (BE FAST) • Balance loss • Eyes: vision
Management Algorithm Clinical ... FAST) • Balance loss ... • Eyes: vision loss
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
Pathogenesis and clinical ... event -> Complete loss ... Loss of pain and ... Sensory loss below ... -> Ipsilateral loss
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