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diagnosis causes hypokalemia pharmacology renal treatment algorithm binders binding comparison crrt diuresis diuretics excretion gitelman k managment modalities modes pathophysiology
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... patients sensitive to high ... of aspiration #Potassium ... #medications #pharmacology ... #table #comparison
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... Clenching of fist during ... phlebotomy High ... Medications 2. ... #high #nephrology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... Clenching of fist during ... phlebotomy High ... Medications 2. ... #high #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Rhabdomyolysis - Differential ... Framework and Management ... Monitor potassium ... per day until stable ... causes #treatment #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Etiology: • Medications ... Elimination (see Table ... STOP offending medications ... #Treatment #potassium ... #nephrology #K
Pragmatic diagnostic algorithm for hypokalemia. ***Typical presentations: • Vomiting: urine Na/Cl > 1.6, low urine
urine Na/Cl < 0.7, high ... correcting serum potassium ... Other medications ... #diagnosis #differential ... #algorithm #nephrology
Renal Replacement Therapy (RRT) - ICU One Pager Summary Indications (AIEOU): • A: Acidosis (usually severe metabolic)
derangements (hyperkalemia ... , hypercalcemia, ... High clearance achieved ... #Therapy #RRT #managment ... #nephrology #CRRT
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
irrigation • Management ... Loop Diuretics; High-Ceiling ... Hyponatremia • Hypercalcemia ... #Pharmacology #Medications ... #Table
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
hypokalemic salt-losing ... (renal potassium ... ratio 0.5%) Differential ... Syndrome #diagnosis #nephrology ... #management #pathophysiology
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