22 results
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Dosing: Initial ... binds magnesium • Dosing ... and calcium • Dosing ... ); nausea, vomiting ... #pharmacology #table
Causes of Hyponatremia - Differential Diagnosis Algorithm
Hypovolemia, UNa > 20: 
 • Renal losses, Diuretic excess,
Causes of Hyponatremia ... deficiency, Salt-losing ... renal failure Hypervolemia ... Diagnosis #Algorithm #Causes ... #nephrology
Reflex Testing - Causes of Hyporeflexia and Hyperreflexia
Focal Hyporeflexia: 
 • Radiculopathy, Mononeuropathy, Polyneuropathy, Acute stroke,
Hyporeflexia: • Hypercalcemia ... Guillain-Barré syndrome ... Hyperthyroidism, Serotonin syndrome ... differential #diagnosis #table ... #neurology
Classification, Differential Diagnosis, and Features of Hyponatremia According to Volume Status 

Hypervolemic hypernatremia 
 - CHF
- Nephrotic syndrome ... Glucocorticoid deficit - Hypokalemia ... deficit - Salt-losing ... Differential #Diagnosis #Table ... #Causes
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... recessive salt-losing ... thiazide-sensitive sodium-chloride ... H+ secretion → Hypokalemia ... Pathophysiology #nephrology
Drugs associated with hypokalemia and hypomagnesemia

Hypokalemia
- Shift from extracellular fluid to intracellular fluid compartment
  -
associated with hypokalemia ... overdose) - Sodium ... renal Fanconi syndrome ... differential #diagnosis #nephrology ... #Causes #hypomg
Hyponatremia - Differential Diagnosis Algorithm
Hypovolemic - Give volume
Hypervolemic (Edematous) - Look for and treat underlying cause
treat underlying cause ... cirrhosis, nephrotic syndrome ... Pulmonary Diseases ... Algorithm #diagnosis #nephrology ... #sodium
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
time you have a case ... : Hypovolemia, Hypervolemia ... Cirrhosis, Nephrotic syndrome ... differential #diagnosis #table ... #sodium #nephrology
Hyponatremia - Differential Diagnosis by Mechanism
Decr Blood Pressure (“Decr Effective Circulating Volume”) 
 - Volume depletion
- Cirrhosis Syndrome ... hemorrhage) - Pulmonary ... Differential #Diagnosis #Table ... #Causes #Sodium
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... Clenching of fist during ... - Tumor lysis syndrome ... differential #diagnosis #causes ... potassium #high #nephrology