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Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
and sodium • Dosing ... binds magnesium • Dosing ... and calcium • Dosing ... #medications #pharmacology ... #table #comparison
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Clenching of fist during ... : • CKD • Poorly ... deficiency • Renal ... Type IV RTA • Renal ... potassium #high #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Clenching of fist during ... : • CKD • Poorly ... deficiency • Renal ... Type IV RTA • Renal ... potassium #high #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
- Renal Failure ... VBG (acidosis), CK ... 15 suggests ↓ renal ... Elimination (see Table ... #potassium #nephrology
Phosphate binders - quick reference chart of maximum daily dose. Most patients with CKD will require
since they are not able ... restricted due to hypercalcemia ... #Nephrology #PhosphateBinders ... Hyperphosphatemia #Dose #Dosing ... #Pharmacology #
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Management of Hyperkalemia ... Binders #Management #Hyperkalemia ... #treatment #pharmacology ... #table #comparison ... #nephrology
Veltassa (Patiromer) 
MECHANISM: Potassium Binder 
INDICATION: Treatment of Hyperkalemia 
FORMULATION: Powder for oral suspension 
DOSING: 8.4
INDICATION: Treatment ... oral suspension DOSING ... needed, based on K ... patients with CKD ... #Pharmacology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Torsemide) • Acute pulmonary ... Hyponatremia • Hypercalcemia ... Tolvaptan) • Treatment ... #Pharmacology # ... Medications #Table