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differential pharmacology nephrology causes management high summary anticholinergics antiepileptic antiseizure binders binding bradi bradycardia cardiology checklist coagulation compared deficiencies deficiency
Antiseizure Drugs Sodium Channel Blockers: Carbamazepine, Oxcarbazepine, Eslicarbazepine, Lamotrigine, Lacosamide, Phenytoin, fosphenytoin Broad Spectrum: Valproate, Levetiracetam, Brivaracetam,
Antiseizure Drugs ... Tiagabine, Vigabatrin Potassium ... antiepileptic #medications ... #pharmacology #comparison ... #table
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... Hyperkalemia ... #differential #diagnosis ... #pharmacology #potassium ... #medications #druginduced
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... Agents to Treat Hyperkalemia ... of aspiration #Potassium ... #medications #pharmacology ... #table #comparison
Vasopressors and Inotropes • Norepinephrine - Levophed - "Levo" - Generally thought of as the first
pressor added in shock ... Inotropes #management #criticalcare ... #summary #comparison ... #table #pharmacology ... #indications
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Diagnosis Framework ... reactions Common Drugs ... • Recent IV potassium ... Medications 2. ... #causes #potassium
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Diagnosis Framework ... reactions Common Drugs ... • Recent IV potassium ... Medications 2. ... #causes #potassium
A toxidrome is a syndrome (set of symptoms) caused by specific medications or toxins. There are 5
caused by specific medications ... barbituates, “Z-drugs ... antihistamines #Diagnosis ... Toxicology #Toxidromes #Comparison ... #Table #Anticholinergics
Bradycardia - Differential Diagnosis Framework BRADI Mnemonic • BRASH/Hyperkalemia • Reduced oxygen/Glucose/Temp • ACS • Drugs •
- Differential Diagnosis ... Temp • ACS • Drugs ... blocking agent • Shock ... Heart block Medications ... #differential #diagnosis
Shock - Differential Diagnosis Framework MAP = CO x SVR Hypovolemic (↓ Intravascular volume): • Hemorrhage, dehydration due
Shock - Differential ... Diagnosis Framework ... adrenal crisis, drugs ... #table #comparison ... #criticalcare
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
Anticoagulant Medications ... Acute DIC - Septic shock ... Deficiencies #Summary #table ... #comparison #diagnosis
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