777 results
Adrenal Insufficiency Differential Diagnosis Algorithm
Clinical suspicion: Weakness, fatigue, nausea, musculoskeletal pain, dizziness, volume depletion, abdominal pain,
hyperkalemia, hyperpigmentation ... baseline ACTH - Primary
CLINICAL MANIFESTATIONS 
OF ADRENAL INSUFFICIENCY. 

Primary and secondary adrenal insufficiency:
 - Tiredness, weakness, mental depression
Primary and secondary ... eosinophilia Primary ... disorders: - Hyperpigmentation
Adrenal Insufficiency - Diagnosis and Management Summary
Primary Adrenal Insufficiency:
Most Common Cause in the US: Autoimmune Adrenalitis
Other
Management Summary Primary ... pain (10-40%), hyperpigmentation ... Hyperpigmentation ... Insufficiency #Primary
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary ... Examination: • Skin hyperpigmentation ... Drug-induced cholestasis, Primary ... malignancy #Primary
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
Primary Adrenal ... endocrine disorder - Primary ... hypothyroidism - Primary ... Deficiency: Signs • Hyperpigmentation ... IF < 18 ug/dL Primary
Adrenal Crisis
Do not confuse acute adrenal crisis with Addison disease. In 1855, Thomas Addison described a
weight loss, and hyperpigmentation ... as the primary ... common cause of primary
Disorders of Pigmentations - Hypopigmentation and Hyperpigmentation - Differential Diagnosis Algorithm

HYPOPIGMENTATION
Diffuse Congenital - Generalized hypopigmentation of
Pigmentations - Hypopigmentation ... and Hyperpigmentation ... HYPERPIGMENTATION ... #Hypopigmentation ... #Hyperpigmentation
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features
1) Skin
 • Thin, easily bruisable skin with
hypercortisolism: often hyperpigmentation ... Hyperpigmentation ... not a feature of primary ... Imaging: 1) Primary
Cutaneous signs of Addison's disease may be a useful clue. Hyperpigmentation especially involves sun-exposed areas and
Hyperpigmentation ... often have patchy hyperpigmentation ... flexural on oral hyperpigmentation
Skin Hypopigmentation - Differential Diagnosis Algorithm

Diffuse Congenital - Generalized hypopigmentation of hair, eyes, skin
 • Phenylketonuria
Skin Hypopigmentation ... - Generalized hypopigmentation ... Post-inflammatory hypopigmentation ... #Hypopigmentation