677 results
Disorders of Pigmentations - Hypopigmentation and Hyperpigmentation - Differential Diagnosis Algorithm

HYPOPIGMENTATION
Diffuse Congenital - Generalized hypopigmentation of
Pigmentations - Hypopigmentation ... and Hyperpigmentation ... of hair, eyes, skin ... HYPERPIGMENTATION ... #disorders #skin
Skin Hypopigmentation - Differential Diagnosis Algorithm

Diffuse Congenital - Generalized hypopigmentation of hair, eyes, skin
 • Phenylketonuria
Skin Hypopigmentation ... - Generalized hypopigmentation ... of hair, eyes, skin ... #Hypopigmentation ... #disorders #skin
Cutaneous signs of Addison's disease may be a useful clue. Hyperpigmentation especially involves sun-exposed areas and
Hyperpigmentation ... often have patchy hyperpigmentation ... patients with darker skin ... flexural on oral hyperpigmentation
Generalized Hyperpigmentation Differentials
Use the Mnemonic "no skin SPARED"

Images from dermnet.nz and merckmanuals

Mnemonic from https://www.medscape.com/slideshow/dermatology-mnemonics-6011359#5 #diagnosis #differential
Generalized Hyperpigmentation ... the Mnemonic "no skin ... #dermatology #skin
Skin Hyperpigmentation - Differential Diagnosis Algorithm
Diffuse:
 • Tanning
 • Adverse cutaneous drug eruption
 • Addison's disease
Skin Hyperpigmentation ... Post-Inflammatory hyperpigmentation ... #Hyperpigmentation ... #disorders #skin
Physiologic Skin Changes in Pregnancy - Differential Diagnosis Algorithm

Face
 • Melasma
Abdomen
 • Linea Nigra 
Hormone induced
Physiologic Skin ... Hormone induced • Hyperpigmentation ... number (probable) Skin ... normal #Pregnancy #skin
Diffuse Melanosis Cutis - Several weeks earlier, a progressive gray–blue discoloration of the skin had developed.
discoloration of the skin ... pronounced change in skin ... MelanosisCutis #Hyperpigmentation
Testicular Cancer - Treatment Related Toxicities

Bleomycin, Cisplatin, Etoposide, lfosfamide
Tinnitus & Hearing Loss
Neurotoxicity
Pulmonary Fibrosis
Hypotension
Nephrotoxicity
Skin Hyperpigmentation
Hemorrhagic Cystitis
Myelosuppression
Peripheral Neuropathy

Ashley
Nephrotoxicity Skin ... Hyperpigmentation
CLINICAL MANIFESTATIONS 
OF ADRENAL INSUFFICIENCY. 

Primary and secondary adrenal insufficiency:
 - Tiredness, weakness, mental depression
disorders: - Hyperpigmentation ... disorders: - Pale skin
Congenital Adrenal Hyperplasia - 21-Hydroxylase Deficiency - Signs and Symptoms
 • Brain: Androgenization effects, Glucocorticoid effects,
gonadal failure • Skin ... : Hyperpigmentation