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diagnosis differential algorithm pathophysiology hematology management endocrinology causes hemophagocytic lymphohistiocytosis menstrualcycle rheumatology treatment disease ovariancycle primarycare signs symptoms syndrome workup
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Lymphohistiocytosis (HLH ... / Diagnosis: HLH ... Elevated CXCL9 • Hypertriglyceridemia ... If no response HLH ... TheIDtrivia #HLH
Hemophagocytic Lymphohistiocytosis (HLH) Diagnostic Criteria - 2004 vs 2009 At least three of the following: -
Lymphohistiocytosis (HLH ... required) - Hypertriglyceridemia ... @PulmCrit #HLH
Hypertriglyceridemia - Ultrafiltrate after Plasmapheresis #Clinical #Photo #Hypertriglyceridemia #Ultrafiltrate #Plasmapheresis
Hypertriglyceridemia ... Clinical #Photo #Hypertriglyceridemia
Hemophagocytic Lymphohistiocytosis (HLH) Clinical Features: Fever, Splenomegaly, Hepatomegaly, Lymphadenopathy, Confusion Classic lab findings in HLH: ↑↑ ferritin, Anemia,
Lymphohistiocytosis (HLH ... lab findings in HLH ... Diagnostic Criteria for HLH ... consistent with HLH ... EricsMedicalLectures/ #HLH
Familial Dyslipidemias • Hyperchylomicronemia • Familial hypercholesterolemia • Dysbetalipoproteinemia • Hypertriglyceridemia Sarah Lyon @sarahthelyon #Familial #Dyslipidemias #lipidemia #cardiology
Dysbetalipoproteinemia • Hypertriglyceridemia
Metabolism of plasma lipoproteins and related genetic diseases - Familial Hypercholesterolemia Type I (FAMILIAL HYPERCHYLOMICRONEMIA) Type IIA
Type IV (FAMILIAL HYPERTRIGLYCERIDEMIA ... FAMILIAL MIXED HYPERTRIGLYCERIDEMIA
Diagnostic Schema for Hyperferritinemia Pearl: Diseases associated with extreme elevations: 1. HLH 2. Still's disease 3. Systemic
HLH 2.
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH ... assessment+++ Primary HLH ... • Familial HLH ... XLP) Acquired HLH ... Nicolas Taar #HLH
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
and Screen for HLH ... HLH syndrome 5.
Proposed Treatment Algorithm for MAS / HLH #MAS #HLH #Hemophagocytic #Lymphohistiocytosis #Management #Treatment #Algorithm #Hematology
Algorithm for MAS / HLH ... #MAS #HLH #Hemophagocytic
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