46 results
Compelling and Possible Contraindications to Antihypertensive Drugs
Diuretics (thiazides)
 - Gout
 - Metabolic syndrome, Glucose intolerance, Pregnancy,
, Hypokalemia, Erectile ... failure - Co-medication ... Pgp-dependent drugs (e.g ... antihypertensive #medications ... contraindications #table
Etiologies of Hypernatremia - Differential Diagnosis
GI losses / Insensible losses
Sodium Overload
Transcellular Movement of Water
Central Diabetes Insipidus
in kidneys) - Medications ... cisplatin) - Chronic hypercalcemia ... - Chronic hypokalemia ... Differential #Diagnosis #Table ... #Causes
Constipation - Differential Diagnosis Algorithm
Diet/Lifestyle
 • Fibre
 • Calories
 • Fluid
 • Exercise
 • Psychosocial
Medications
 •
Psychosocial Medications ... Neurally Active Medications ... Hypothyroidism • Hypokalemia ... • Hypercalcemia ... Diagnosis #Algorithm #Causes
Shock - Differential Diagnosis by Classification
Reflex Syncope 
 - Vasovagal syncope
   • Prolonged standing
stenosis • Hypertrophic ... depletion - Medication ... Alcohol blackout - Medication ... Classification #Table ... #Causes
Hyperkalemia shortens repolarization; changes in the T wave provide the earliest clues to hyperpotassemia.
 - At
Hyperkalemia shortens ... repolarization causes ... #Diagnosis #Hyperkalemia ... #EKG #ECG #Changes ... #Progression #Table
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
Renal Loses - Medications ... abnormalities - Hypercalcemia ... - Hypokalemia ... Low #Magnesium #Table ... Classification #Causes
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Agents to Treat Hyperkalemia ... constipation, diarrhea, nausea ... ); nausea, vomiting ... #medications #pharmacology ... #table #comparison
Reflex Testing - Causes of Hyporeflexia and Hyperreflexia
Focal Hyporeflexia: 
 • Radiculopathy, Mononeuropathy, Polyneuropathy, Acute stroke,
Reflex Testing - Causes ... Hyporeflexia: • Hypercalcemia ... Deep coma (any cause ... polyneuropathy (e.g ... differential #diagnosis #table
Medications for the Treatment of Hyperkalemia
The goals of acute treatment are to prevent potentially life-threatening cardiac
intervention are symptoms ... , changes on ECG ... , and Table 3 summarizes ... medications used ... #Management #Medications
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... Lysis Syndrome: • Pathophysiology ... hydration - Hyperkalemia ... unless worrisome EKG