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diagnosis differential adrenal hirsutism hypercalcemia insufficiency rheumatology vasculitis acth associated breast champs classification discharge glomerulonephritis hematology highthyroid hyperthyroidism hyponatremia malignancy
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... @AnnKumfer #Hypocomplementemia ... #Low #Complement
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low ... Complement: Post-strep ... Idiopathic • Normal Complement ... differential #diagnosis #algorithm
Hypercalcemia - Differential Diagnosis Algorithm Elevated PTH (High or normal): • Primary Hyperparathyroidism • Familial Hypocalciuric Hypercalcemia Low
Differential Diagnosis Algorithm ... Hypercalcemia Low ... Differential #Diagnosis #Algorithm ... #causes #endocrinology
Breast Discharge - Differential Diagnosis Algorithm High Prolactin + Normal TSH • Microprolactinoma • Steroid Hormone Intake
Differential Diagnosis Algorithm ... Prolactin + Normal/ Low ... Differential #Diagnosis #Algorithm ... #Endocrinology ... #Causes
Hirsutism & Virilization - Differential Diagnosis Algorithm ADRENAL EXCESS Ovarian • Polycystic Ovarian Syndrome • Hyperthecosis • Tumor Adrenal
Differential Diagnosis Algorithm ... Syndrome Tumor Low ... Differential #Diagnosis #Algorithm ... #endocrinology ... #causes
Hyperthyroidism - Differential Diagnosis Algorithm High/Normal Radioiodine Uptake - Autoimmune Thyroid Disease: • Grave's
Differential Diagnosis Algorithm ... Trophoblastic Neoplasm Low ... Differential #Diagnosis #Algorithm ... #endocrinology ... #causes
Adrenal Insufficiency Differential Diagnosis Algorithm Clinical suspicion: Weakness, fatigue, nausea, musculoskeletal pain, dizziness, volume depletion, abdominal pain,
Differential Diagnosis Algorithm ... Weakness, fatigue, nausea ... Baseline plasma ACTH Low ... insufficiency • Low ... #endocrinology
Hirsutism - Differential Diagnosis Algorithm RAPID ONSET Medications • Steroids • Danazol • Progestin Containing Contraceptives Increased Serum Testosterone
Differential Diagnosis Algorithm ... Adrenal Neoplasm SLOW ... Differential #Diagnosis #Algorithm ... #endocrinology ... #causes
Adrenal Insufficiency Diagnosis Algorithm - Evaluation of HPA Axis Response to ACTH Early am cortisol < 3
Insufficiency Diagnosis Algorithm ... unclear (often the case ... primary AI - Low ... Insufficiency #Diagnosis #Algorithm ... Stimulation #Test #Endocrinology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement ... (Low levels mixed
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