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diagnosis differential rheumatology nephrology lupus management nephrotic testing vasculitis classification druginduced erythematosus glomerulonephritis hematology initial nephritic nephritis polycythemia proteinuria summary
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... 90% - Low complement ... • Immunologic Workup ... Evolution: Chronic disease ... #comparison #table
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... • Drugs Glomerular ... (MPA) • SLE ... Minimal change disease ... #Causes
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE ... • Immunologic Workup ... Positive in 60-80% of cases ... 80% - Low complement ... Evolution: Chronic disease
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... Vasculitis - Skin, glomeruli ... : - Kidneys: glomerular ... against MPO • Complement ... vasculitis, and SLE
Recommended initial testing for patients being evaluated for glomerular disease 24-hour urine collection - Quantify proteinuria.
disease 24- ... or alternative complement ... infections are common causes ... of glomerular disease ... #testing #workup
Recommended initial testing for patients being evaluated for glomerular disease 1) 24-hour urine collection - Quantify proteinuria.
or alternative complement ... infections are common causes ... of glomerular disease ... #glomerular #disease ... #workup #diagnosis
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
, such as SLE, atherosclerotic ... • Kidneys: Non-glomerular ... tract, and often causes ... Elevated AST ALT • Hypocomplementemia ... Vasculitis) • Hypocomplementemic
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Differential Diagnosis Algorithm ... an underlying cause ... some time, let’s see ... As with many disease ... #workup #hematology
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