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diagnosis differential rheumatology nephrology glomerular glomerulonephritis lupus management sle testing vasculitis ascites comparison disease druginduced erythematosus exudative gammopathy hyponatremia initial
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low ... Complement: Post-strep ... GN, Lupus Nephritis ... differential #diagnosis #algorithm
Suggested diagnostic approach to a patient with exudative ascites. Low ascitic fluid protein should direct practitioners
Low ascitic fluid ... syndrome as a cause ... obstruction, nephrotic ... ascites #diagnosis #workup ... #algorithm #differential
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
ulcers, Lupus nephritis ... • Immunologic Workup ... Positive in 60-80% of cases ... 60-80% - Low ... complement - 50
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... in >90% - Low ... complement - Rare ... Discontinuation of causal ... ulcers, Lupus nephritis
Recommended initial testing for patients being evaluated for glomerular disease 24-hour urine collection - Quantify proteinuria.
in monitoring low-level ... or alternative complement ... infections are common causes ... glomerular #testing #workup ... #nephritic #nephrology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... Urticaria and hypocomplementemia ... against MPO • Complement ... (Low levels mixed ... #rheumatology #classification
Recommended initial testing for patients being evaluated for glomerular disease 1) 24-hour urine collection - Quantify proteinuria.
in monitoring low-level ... or alternative complement ... infections are common causes ... glomerular #disease #workup ... #nephritis
Hyponatremia - Differential Algorithm Isotonic Hyponatremia: Hyperlipidemia, Hyperproteinemia, Recent TURP Hypotonic Hyponatremia: • Hypovolemia: Diuretics/Nephropathies, Vomiting, Diarrhea,
- Differential Algorithm ... Liver Cirrhosis, Nephrotic ... MH/CCF/CWRU EM ... #diagnosis #causes ... nephrology #sodium #low
Monoclonal Gammopathy of Renal Significance (MGRS) MGRS • MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
kidney disease caused ... Diagnostic Workup ... guide subtype classification ... Damages Kidneys • Low ... tubulopathy) - Complement
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