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rheumatology diagnosis management druginduced sle comparison differential dil erythematosus nephritis nephrology summary systemic table vasculitides vasculitis
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
• Immunologic Workup ... 80% - Low complement ... life-threatening • Treatment ... management of SLE • Evolution ... : Chronic disease
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... 90% - Low complement ... • Immunologic Workup ... 80% - Low complement ... : Chronic disease
Management of Lupus Nephritis Lupus nephritis (LN) in 10 to 40% of SLE Hallmark = proteinuria 20.5 g/g
Nephritis Lupus ... renal histological evaluation ... severity (ISN/RPS classification ... by 12 months Classification ... Nephritis #Management #treatment
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Eosinophilia, asthma, chronic ... inflammation Others: • Lupus ... such as systemic lupus ... against MPO • Complement ... #rheumatology #classification
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
• Immunologic Workup ... 90% - Low complement ... constitutional symptoms • Treatment ... cutaneous-DIL • Evolution ... rheumatology #diagnosis #treatment
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