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differential causes hematology rheumatology management nephrology anemia sle types dermatology pediatrics peds renal testing vasculitis allergy cardiology endocrinology erythematosus glomerulonephritis
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... Chain deposition disease ... S - Systemic Lupus ... #Low #Complement ... CHAMPS #Mnemonic #diagnosis
Lupus Nephritis Classification Algorithm #Lupus #Nephritis #Classification #Algorithm #diagnosis #differential #types #rheumatology #nephrology #renal
Lupus Nephritis ... Classification Algorithm ... #Lupus #Nephritis ... #Classification ... #Algorithm #diagnosis
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... • Immunologic Workup ... 80% - Low complement ... Evolution: Chronic disease ... Erythematosus #Diagnosis
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
staining): • Low Complement ... Post-strep GN, Lupus ... involvement: Anti-GBM Disease ... #differential #diagnosis ... #algorithm #rheumatology
Kawasaki Disease - Workup and Diagnostic Algorithm #Diagnosis #Management #Peds #Pediatrics #Kawasaki #Disease #Algorithm #CRASH #BURN
Kawasaki Disease ... - Workup and Diagnostic ... Algorithm #Diagnosis ... Pediatrics #Kawasaki #Disease ... #Algorithm #CRASH
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Criteria for Systemic Lupus ... anticoagulant • Complement ... #EULARACR #Classification ... Erythematosus #diagnosis
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... 90% - Low complement ... • Immunologic Workup ... Evolution: Chronic disease ... #rheumatology #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Urticaria and hypocomplementemia ... inflammation Others: • Lupus ... such as systemic lupus ... against MPO • Complement ... #rheumatology #classification
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
Classification of ... - systemic lupus ... dermatomyositis #Size #Classification ... Vasculitis #Vessels #Diagnosis ... #Rheumatology #Diagnosis
Hyperthyroidism (low TSH, High T4/T3) - Diagnostic Algorithm Radioactive iodine scan – get if concern for nodular
Algorithm Radioactive ... Graves disease – ... Graves disease! ... workup choices ... #Algorithm #Workup
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