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diagnosis causes rheumatology vasculitis dermatology petechiae petechial rash anemia classification extravascular glomerulonephritis hemolysis hemolytic immunecompromised immunocompromised intravascular nonpalpable physicalexam progressive
Fever of Unknown Origin (FUO) - Further Workup • CNS symptoms? Get an LP and imaging
Origin (FUO) - ... Further Workup ... Returning Traveler’ algorithm ... values supporting hematologic ... udaygulati #FUO
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
immunofluorescence Immune Complex ... staining): • Low Complement ... Glomerulonephritis #Vasculitis #differential ... #diagnosis #algorithm ... #rheumatology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Diagnosis Algorithm ... perfringens - Complement-Mediated ... Drug-induced immune-complex ... #Diagnosis #Algorithm ... #Causes #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... Diagnosis Algorithm ... bartonella (oroya fever ... #Diagnosis #Algorithm ... #workup #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tracts Immune Complex ... Urticaria and hypocomplementemia ... Coronary arteries - Fever ... Vasculitis: • Fevers ... against MPO • Complement
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Petechial Rash - Differential ... Diagnosis Algorithm ... Red Flags: • Fever ... deficiency Work ... Up: • Complete
Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH These rashes can be especially challenging and are associated with devastating differential
Purpuric Rashes- THE ALGORITHMIC ... petechiae/purpura with fever ... petechiae/purpura with fever ... petechiae require complete ... #Diagnosis #Dermatology
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm Structural Defect - Asplenia/HypospIenism • Bacteremia/Septic
Causes of Fever ... Diagnosis Algorithm ... Periodontal Disease Complement ... Infection #Fever ... #Causes #Hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... pauci-immune GN Immune Complex ... Elevated AST ALT • Hypocomplementemia ... Vasculitis) • Hypocomplementemic ... #Diagnosis #Rheumatology
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