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diagnosis differential rheumatology management renal causes dyspnea erythematosus gammopathy glomerulonephritis lupus mgrs monoclonal pleural progressive prs rapidly rpgn significance sjogrens
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
progressing GN • New pulmonary ... often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement ... #rheumatology #classification
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
staining): • Low Complement ... Idiopathic • Normal Complement ... With associated pulmonary ... Glomerulonephritis #Vasculitis ... differential #diagnosis #algorithm
Causes of Dyspnea - Differential Diagnosis Algorithm Cardiac: • Dysrhythmia • Ischemia • Cardiomyopathy • Valvular disease
Differential Diagnosis Algorithm ... Pneumonia • Pulmonary ... hypertension • Vasculitis ... Pleura: • Pleural effusion ... Differential #Diagnosis #Algorithm
Unilateral Pleural Effusion - Differential Diagnosis and Workup Algorithm Landsberg Manual @LandsbergManual - https://amzn.to/3rEtbK8 #Unilateral #Pleural #Effusion #Differential
Unilateral Pleural Effusion ... Diagnosis and Workup ... Algorithm Landsberg ... Unilateral #Pleural #Effusion ... #Algorithm #pulmonary
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal ... Autoimmune ANCA vasculitis ... palpable purpura 2/2 vasculitis ... mononeuritis multiplex WORKUP ... LVEF, pericardial effusion
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low complements ... Skin Disease Classification ... ANCA-associated vasculitis ... Lungs: • Pleural effusions ... RNP antibodies, Complement
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Cytopenia: 2% • Hypocomplementemia ... thickening or effusion ... , INC risk PE, Pulmonary ... ) • Cutaneous vasculitis ... : 2% Systemic Vasculitis
Monoclonal Gammopathy of Renal Significance (MGRS) MGRS • MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
Diagnostic Workup ... guide subtype classification ... tubulopathy) - Complement ... formation causing vasculitis
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