23 results
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... Membranoproliferative glomerulonephritis ... Post/pauci immune glomerulonephritis ... @AnnKumfer #Hypocomplementemia ... #Low #Complement
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low Complement ... Post-strep GN, Lupus Nephritis ... Idiopathic • Normal Complement ... differential #diagnosis #algorithm
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
Membranoproliferative Glomerulonephritis ... dysmorphic RBC, RBC casts ... MGPN • Complement ... glomerulopathy, radiation nephritis ... Membranoproliferative #Glomerulonephritis
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
Causes of Hematuria ... Differential Diagnosis Algorithm ... • Hereditary nephritis ... and >3.5g/day (nephrotic ... #Causes
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
or alternative complement ... infections are common causes ... #workup #diagnosis ... #glomerulonephritis ... #nephrotic #nephritic
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Kidney Injury - AKI Workup ... Algorithm and Differential ... osmolarity If cause ... and signs • Glomerulonephritis ... • Interstitial nephritis
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Algorithm INDICATIONS ... evaluation or workup ... 1,500 cells/µL Workup ... for secondary causes ... eosinophilia (common causes
Hypereosinophilia Different Diagnosis and Workup
Secondary causes are broad so start with a med review, the most
Diagnosis and Workup ... Secondary causes ... the most common cause ... the US inpatient setting ... #algorithm
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Algorithm - Approach ... membrane; GN = glomerulonephritis ... Nephrocalcinosis causes ... #Algorithm #differential ... #proteinuria #nephrotic
Suggested diagnostic approach to a patient with exudative ascites. Low ascitic fluid protein should direct practitioners
syndrome as a cause ... Although nonhepatic causes ... obstruction, nephrotic ... ascites #diagnosis #workup ... #algorithm #differential