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diagnosis differential hematology dermatology rheumatology nephrology neurology skinrash acute aki classification disorders pulmonary testing ulcers workup eosinophilia glomerular glomerulonephritis injury
Pathophysiology of Hypocomplementemic Urticarial Vasculitis C1q/anti-C1q antibiody -> Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology of Hypocomplementemic ... Urticarial Vasculitis ... Complex Formation - Complement ... Formation -> Vasculitis ... TerrierBen #Hypocomplementemic
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... @AnnKumfer #Hypocomplementemia ... #Low #Complement
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitis and Vasculitides ... tract, and often causes ... often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low Complement ... Idiopathic • Normal Complement ... Glomerulonephritis #Vasculitis ... differential #diagnosis #algorithm
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Mechanism of Action: Allergen-specific ... lgE causes mast-cell ... antigens, leading to complement ... they activate complement ... reactions #types #allergy
Vascular Skin Lesions - Differential Diagnosis Algorithm - Petechiae < 0.2 cm diameter - Purpura 0.2
Differential Diagnosis Algorithm ... • Acquired - Vasculitis ... #Vascular #Vasculitis ... Differential #Diagnosis #Algorithm ... #causes
Cough - Diagnostic Schema Infectious: URTI, LRTI, Bacterial, Viral Irritant/Exposure: Allergic, Post-infectious, Pneumonitis, ACEi, PTX, Foreign Body Airway Disease:
Irritant/Exposure: Allergic ... CHF, Autoimmune Vasculitis ... #Differential #Algorithm
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... When to Consider Vasculitis ... tract, and often causes ... Elevated AST ALT • Hypocomplementemia ... ) • Hypocomplementemic
Causes of Peripheral Weakness with Sensory Changes - Differential Diagnosis Algorithm Radiculopathy: • Disc • Spondylosis •
Causes of Peripheral ... Differential Diagnosis Algorithm ... Multiplex: • Vasculitis ... Differential #Diagnosis #Algorithm ... #Causes
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Differential Diagnosis Algorithm ... perfringens - Complement-Mediated ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
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