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diagnosis hematology differential management blood bruising product reactions anemia anticoagulation c1inh causes coronavirus covid19 esterase hemolytic hemostasis inhibitor mds myelodysplasia
Complement 1 esterase inhibitor (C1-INH) Deficiency Testing Algorithm INDICATIONS FOR TESTING: • Recurrent angioedema (without urticaria) •
Complement 1 esterase ... inhibitor (C1-INH) Deficiency ... Testing Algorithm ... #Testing #Algorithm ... #allergy #diagnosis
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Differential Diagnosis Algorithm ... Sequestration Disordered Platelet ... Coagulation #Bleeding ... Differential #Diagnosis #Algorithm
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Thrombocytosis - Elevated Platelet ... Differential Diagnosis Algorithm ... Acute hemolysis, deficiency ... post-splenectomy, Exercise, Allergic ... Thrombocytosis #Platelets
Complement Deficiency Testing Algorithm • Normal CH50 and AH50 AND High suspicion for complement deficiency •
Complement Deficiency ... Testing Algorithm ... deficiency • Low ... #Deficiency #Testing ... #Algorithm #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
Bleeding and Bruising ... Qualitative defect in platelets ... characteristic of a platelet ... • Bleeding gums ... fibrinogen levels, and testing
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Differential Diagnosis Algorithm ... ' nucleotidase deficiency ... with or without platelet ... Differential #Diagnosis #Algorithm ... workup #hematology #testing
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Crossmatch - involves testing ... - Allergic ... recipients w/ IgA deficiency ... coagulopathy & ↑bleeding ... false negatives on testing
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
unusual bruising or bleeding ... are caused by bleeding ... or folic acid deficiency ... treatments • Copper deficiency ... Treatment: Goals: Treating
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
• Allergic reaction ... recipients w/ IgA deficiency ... common following platelet ... coagulopathy & ↑bleeding ... false negatives on testing
Mount Sinai COVID-19 Anticoagulation Algorithm Inclusion: All admitted patients with COVID-19 Exclusion: High risk of bleeding as judged
Anticoagulation Algorithm ... : High risk of bleeding ... as judged by treating ... , consider: - Platelet ... Anticoagulation #Algorithm
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