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diagnosis differential rheumatology sle vasculitis comparison erythematosus hematology management systemic types allergy anemia champs clinicopathology cryoglobulinemia cryoglobulins druginduced glomerulonephritis high
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... S - Systemic Lupus ... @AnnKumfer #Hypocomplementemia ... #Low #Complement
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low ... Complement: Post-strep ... GN, Lupus Nephritis ... differential #diagnosis #algorithm
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
in >90% - Low ... complement - Rare ... complement - 50 ... • Evolution: Chronic ... sle #comparison #table
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Positive in 60-80% of cases ... 60-80% - Low ... complement - 50 ... • Evolution: Chronic
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Differential Diagnosis Algorithm ... Low Mean Corpuscular ... #Anemia #MCV #Classification ... #Causes #Hematology
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Summary table of ... Allergen-specific lgE causes ... glomerulonephritis, Systemic lupus ... types #allergy #table ... #classification
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Eosinophilia, asthma, chronic ... tract, and often causes ... against MPO • Complement ... (Low levels mixed ... #rheumatology #classification
Hypomagnesemia - Etiologies by Mechanism Decreased GI Uptake - Poor dietary intake (particularly common in alcoholics)
GI losses - Chronic ... Differential #Diagnosis #Low ... #Magnesium #Table ... #Classification ... #Causes #Workup
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low ... complements and ... Skin Disease Classification ... , lymphopenia, low ... : • Chronic B-cell
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... factor level • Low ... serum C4 complement ... (e.g. systemic lupus ... diagnosis #types #classification
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