11 results
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
antigen, leading to complement ... Complement activation ... Hypersensitivity #Types #Classification ... #Pathophysiology ... Diagnosis #Reactions #Table
Blood Product Components, Contents, Volume and Shelf Life

Whole blood (autologous or directed donations) - RBC and
with about 25 mL ... Plasma proteins, all ... coagulation factors, complement ... Volume #Hematology #Management ... #Table
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... relapse - Amy ... Lymphoproliferative #Disorders #Classification ... #pathophysiology ... #differential #algorithm
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Epidemiology: -10% of all ... 90% - Low complement ... 80% - Low complement ... Usual therapeutic management ... sle #comparison #table
SEPSIS AND SEPTIC SHOCK

DEFINITION AND PATHOPHYSIOLOGY
 • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
DEFINITION AND PATHOPHYSIOLOGY ... • Pathophysiology ... NETs), cytokines, complement ... Measure lactate in all ... INITIAL MANAGEMENT
IGG-4 RELATED DISEASE

WHAT?
 • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
dysfunction PATHOPHYSIOLOGY ... - ↑ IgE, ↓ complement ... • Classification ... mimics excluded MANAGEMENT ... IGG4 #Diagnosis #Management
Perhaps quite too often, the knee-jerk reaction to an elevated Troponin is to call our friends
Troponin is to call ... are typically able ... “one size fits all ... #diagnosis #algorithm ... echocardiogram #management
Perhaps quite too often, the knee-jerk reaction to an elevated Troponin is to call our friends
Troponin is to call ... are typically able ... “one size fits all ... #diagnosis #management ... clinica l#foamed #algorithm
Stepwise management of acute headache in the emergency department 

1) Metoclopramide 10 mg IV or prochlorperazine
Stepwise management ... All medication should ... therapy listed in Table ... #Headache #Management ... #Stepwise #Algorithm
Diets and Inflammatory Bowel Disease (IBD)
Diet affects IBD by 3 mechanisms
1. Microbiome ( ↓ diversity)
2. Mucosal
• Nutrition as complement ... recommended → all ... balanced, nutritious Table ... Nutrition #comparison #table ... #management #treatment