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rheumatology differential lupus pathophysiology renal vasculitis allergy champs cryoglobulinemia cryoglobulins disorders erythematosus gammopathy hypersensitivity igg4 low lymphomas lymphoproliferative management mgrs
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... 1 (50%-80%), type ... #Low #Complement ... CHAMPS #Mnemonic #diagnosis ... #differential #hematology
Lupus Nephritis Classification Algorithm #Lupus #Nephritis #Classification #Algorithm #diagnosis #differential #types #rheumatology #nephrology #renal
Lupus Nephritis Classification ... Algorithm #Lupus ... #Algorithm #diagnosis ... #differential #types ... #rheumatology #
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
cellular antigen, leading ... to complement activation ... Complement activation ... #Classification ... Pathophysiology #Allergy #Diagnosis
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
immune system, leading ... Labs/Diagnosis: ... • Low serum C4 complement ... #types #classification ... #rheumatology #
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential Diagnosis ... Algorithm Hodgkin ... Lymphoproliferative #Disorders #Classification ... pathophysiology #Hematology ... #Diagnosis #NonHodgkin
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... Urticaria and hypocomplementemia ... against MPO • Complement ... #rheumatology # ... classification
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low complements ... Skin Disease Classification ... Differential Diagnosis ... Malignancy (e.g. hematologic ... Kikuchi disease • Type-I
IGG-4 RELATED DISEASE WHAT? • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
• Pancreas: Type ... breast, skin DIAGNOSIS ... - ↑ IgE, ↓ complement ... • Classification ... #IGG-4 #IGG4 #Diagnosis
Monoclonal Gammopathy of Renal Significance (MGRS) MGRS • MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
light-chain ratio Diagnostic ... guide subtype classification ... tubulopathy) - Complement ... vasculitis Types ... #Significance #Diagnosis
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