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diagnosis rheumatology differential types allergy hypersensitivity sle table causes erythematosus vasculitis allergic champs criteria cryoglobulinemia cryoglobulins definitions dermatology diseases druginduced
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... glomerulonephritis (>90%) S - Systemic ... Lupus Erythematosus ... @AnnKumfer #Hypocomplementemia ... #Low #Complement
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
they activate complement ... glomerulonephritis, Systemic ... lupus erythematosus ... allergy #table #classification ... #comparison
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Criteria for Systemic ... anticoagulant • Complement ... #EULARACR #Classification ... Criteria #SLE #Systemic
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
complexes • Ex: Systemic ... Lupus Erythematosus ... Dermatitis (ie. reaction ... Allergy #Allergic #Reactions ... #Types #Classification
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
- Local and systemic ... Complement activation ... lupus erythematosus ... Hypersensitivity #Types #Classification ... Allergy #Diagnosis #Reactions
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions - Inflammatory
Differential Diagnosis Algorithm ... Bullous impetigo - Reaction ... • Bullous systemic ... lupus erythematous ... diabeticorum) - Reaction
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammation Others: • Lupus ... lupus erythematosus ... disease, drug reactions ... against MPO • Complement ... #rheumatology #classification
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... 90% - Low complement ... months to years) Systemic ... 80% - Low complement ... #sle #comparison
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... anti-Smith Ab, low complements ... Skin Disease Classification ... Neuropsychiatric systemic ... RNP antibodies, Complement
Causes of Interstitial Lung Disease - Differential Diagnosis Algorithm Idiopathic Interstitial Pneumonia • (UIP) Usual Interstitial Pneumonia
Differential Diagnosis Algorithm ... hypersensitivity) reaction ... Rheumatoid Arthritis, Systemic ... Lupus and Scleroderma ... Differential #Diagnosis #Algorithm
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